Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Aurothioglucose [USP]
RN: 12192-57-3
UNII: 2P2V9Q0E78
InChIKey: MSCUYDPRQMSUFW-BMZZJELJSA-N

Note

  • A thioglucose derivative used as an antirheumatic and experimentally to produce obesity in animals.

Molecular Formulas

  • C6-H11-Au-O5-S
  • C6-H11-O5-S.Au

Molecular Weight

  • 392.1839
 

Classification Codes

Classification Codes

  • Antirheumatic
  • Antirheumatic Agents
  • Drug / Therapeutic Agent
  • Human Data
  • Reproductive Effect
  • Tumor Data

Superlist Classification Code

  • Overall Carcinogenic Evaluation: Group 3
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Aurothioglucose
  • Aurothioglucose [USP]

MeSH Heading

  • Aurothioglucose

Synonyms

  • (1-D-Glucosylthio)gold
  • (1-Thio-D-glucopyranosato)gold
  • (D-Glucopyranosylthio)gold
  • 1-Aurothio-D-glucopyranose
  • 1-Thio-D-glucopyranose, gold complex
  • 1-Thio-D-glucopyranose, monogold(1+) salt
  • 1-Thio-glucopyranose, monogold(1+) salt
  • Aureotan
  • Auromyose
  • Aurotan
  • Aurothioglucose
  • Aurumine
  • Authron
  • Brenol
  • CCRIS 59
  • EINECS 235-365-7
  • Glysanol B
  • Gold thioglucose
  • Gold, (D-glucopyranosylthio)-
  • Goldthioglucose
  • GTG
  • HSDB 7174
  • Oronol
  • Romosol
  • SKF 10056
  • Solganal
  • Solganal B
  • Thioglucose d'or
  • Thioglucose d'or [French]
  • UNII-2P2V9Q0E78

Systematic Names

  • (alpha-D-Glucopyranosylthio)gold
  • Aurothioglucose
  • Gold, (1-(thio-kappaS)-D-glucopyranosato-kappaO2)-
  • Gold, (1-thio-D-glucopyranosato)-
  • Gold, (1-thio-D-glucopyranosato-O2,S1)-

Superlist Name

  • Aurothioglucose

Registry Numbers

CAS Registry Number

  • 12192-57-3

FDA UNII

  • 2P2V9Q0E78

Other Registry Numbers

  • 28791-49-3
  • 30398-23-3
  • 61-86-9
  • 6815-94-7
  • 7219-80-9
  • 74144-40-4

System Generated Number

  • 0012192573

Molecular Formulas

Molecular Formulas

  • C6-H11-Au-O5-S
  • C6-H11-O5-S.Au

Molecular Formula Fragments

  • Au
  • C6-H11-O5-S
  • COMPONENT

Structure Descriptors

InChI

1S/C6H11O5S.Au/c7-1-2-3(8)4(9)5(10)6(12)11-2;/h2-9,12H,1H2;/q-1;+1/t2-,3-,4+,5-,6?;/m1./s1

InChIKey

MSCUYDPRQMSUFW-BMZZJELJSA-N

Smiles

C([C@@H]1[C@H]([C@@H]([C@@H]2C(O1)[SH-][Au+]O2)O)O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
chicken LD50 intravenous 1gm/kg (1000mg/kg)   Poultry Science. Vol. 52, Pg. 926, 1973.
chicken LDLo intramuscular 300mg/kg (300mg/kg) SPINAL CORD: OTHER DEGENERATIVE CHANGES

BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES
Toxicology and Applied Pharmacology. Vol. 35, Pg. 223, 1976.
man LDLo unreported 3mg/kg (3mg/kg)   Sammlung von Vergiftungsfaellen. Vol. 10, Pg. 101A, 1939.
man TDLo intramuscular 3357ug/kg/4W- (3.357mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE Journal of Rheumatology. Vol. 12, Pg. 619, 1985.
man TDLo intramuscular 5500ug/kg/10W (5.5mg/kg)   Southern Medical Journal. Vol. 88, Pg. 644, 1995.
man TDLo intramuscular 5500ug/kg/10W (5.5mg/kg) LUNGS, THORAX, OR RESPIRATION: COUGH

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Southern Medical Journal. Vol. 88, Pg. 644, 1995.
mouse LD50 intraperitoneal 2gm/kg (2000mg/kg)   Proceedings of the Society for Experimental Biology and Medicine. Vol. 70, Pg. 498, 1949.
mouse LD50 intraperitoneal 2gm/kg (2000mg/kg)   Proceedings of the Society for Experimental Biology and Medicine. Vol. 70, Pg. 498, 1949.
mouse LD50 intraperitoneal 2gm/kg (2000mg/kg) LIVER: OTHER CHANGES Proceedings of the Society for Experimental Biology and Medicine. Vol. 70, Pg. 498, 1949.
mouse LDLo subcutaneous 1650mg/kg (1650mg/kg)   Experimental Medicine and Surgery. Vol. 3, Pg. 146, 1945.
women TDLo intramuscular 2600ug/kg/15D (2.6mg/kg) LIVER: OTHER CHANGES

GASTROINTESTINAL: NAUSEA OR VOMITING
Arthritis and Rheumatism. Vol. 27, Pg. 230, 1984.
women TDLo intramuscular 14402ug/kg/2Y (14.402mg/kg) KIDNEY, URETER, AND BLADDER: PROTEINURIS

KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"

KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION
Taisha. Molecular Medicine Vol. 12, Pg. 1435, 1975.
women TDLo parenteral 2700ug/kg/4W- (2.7mg/kg) LIVER: "JAUNDICE, CHOLESTATIC" Journal of Rheumatology. Vol. 11, Pg. 843, 1984.

Physical Properties

Physical Property Value Units Temp (deg C) Source
log P (octanol-water) -2.50E+00 (none)   EXP
Water Solubility 4.67E+05 mg/L 25 EST
Vapor Pressure 3.21E-10 mm Hg 25 EST
Atmospheric OH Rate Constant 1.67E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.