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Substance Name: Phentermine [USAN:INN:BAN]
RN: 122-09-8
UNII: C045TQL4WP
InChIKey: DHHVAGZRUROJKS-UHFFFAOYSA-N
Note
- A central nervous system stimulant and sympathomimetic with actions and uses similar to those of DEXTROAMPHETAMINE. It has been used most frequently in the treatment of obesity.
Molecular Formula
- C10-H15-N
Molecular Weight
- 149.2355
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- Classifications
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- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
Classification Codes
- Adrenergic Agents
- Anorexic
- Anti-Obesity Agents
- Appetite Depressants
- Autonomic Agents
- Central Nervous System Agents
- Central Nervous System Stimulants
- Human Data
- Mutation Data
- Neurotransmitter Agents
- Peripheral Nervous System Agents
- Sympathomimetics
Superlist Classification Codes
- DEA Schedule IV
- Reportable Quantity (RQ) = 5000 lb
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Names and Synonyms
Name of Substance
- Phentermine
- Phentermine [USAN:INN:BAN]
MeSH Heading
- Phentermine
Synonyms
- 1,1-Dimethyl-2-phenylethylamine
- 2-Amino-2-methyl-1-phenylpropane
- 2-Phenyl-tert-butylamine
- 4-12-00-02820 (Beilstein Handbook Reference)
- alpha,alpha-Dimethyl-beta-phenylethylamine
- alpha,alpha-Dimethylbenzeneethanamine
- alpha,alpha-Dimethylphenethylamine
- alpha-Benzylisopropylamine
- BRN 0970319
- Duromine
- EC 204-522-1
- EINECS 204-522-1
- Ethanamine, 1,1-dimethyl-2-phenyl-
- Fastin
- Fentermina
- Fentermina [INN-Spanish]
- HSDB 3158
- Ionamin
- Linyl
- Lipopill
- Lonamin
- Mirapront
- Normephentermine
- Obermine
- Omnibex
- Phentermine
- Phenterminum
- Phenterminum [INN-Latin]
- Phentrol
- Phentrol 2
- Phentrol 3
- Phentrol 4
- Phenyl-tert-butylamine
- Phenyl-tertiary-butylamine
- RCRA waste number P046
- UNII-C045TQL4WP
- Wilpo
Systematic Names
- Benzeneethanamine, alpha,alpha-dimethyl-
- Phenethylamine, alpha,alpha-dimethyl-
- Phentermine
Superlist Names
- alpha,alpha-Dimethylphenethylamine
- Benzeneethanamine, alpha,alpha-dimethyl-
- DEA No. 1640
- Phentermine
- RCRA waste no. P046
Registry Numbers
CAS Registry Number
- 122-09-8
FDA UNII
- C045TQL4WP
Other Registry Numbers
- 12674-13-4
- 9008-94-0
Related Registry Number
- 1197-21-3 (hydrochloride)
System Generated Number
- 0000122098
Structure Descriptors
InChI
InChI=1S/C10H15N/c1-10(2,11)8-9-6-4-3-5-7-9/h3-7H,8,11H2,1-2H3InChIKey
DHHVAGZRUROJKS-UHFFFAOYSA-NSmiles
CC(C)Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| man | TDLo | oral | 1429ug/kg (1.429mg/kg) | AUTONOMIC NERVOUS SYSTEM: SYMPATHOMIMETIC | Therapie. Vol. 34, Pg. 205, 1979. |
| mouse | LD50 | intraperitoneal | 71mg/kg (71mg/kg) | Research Communications in Chemical Pathology and Pharmacology. Vol. 14, Pg. 677, 1976. | |
| mouse | LD50 | intravenous | 14mg/kg (14mg/kg) | U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03232, | |
| mouse | LD50 | oral | 105mg/kg (105mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 178, Pg. 62, 1969. |
Physical Properties
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| Boiling Point | 205 | deg C | EXP | |
| log P (octanol-water) | 1.9 | (none) | EXP | |
| Water Solubility | 1.86E+04 | mg/L | 25 | EST |
| Vapor Pressure | 0.096 | mm Hg | 25 | EST |
| Henry's Law Constant | 1.43E-06 | atm-m3/mole | 25 | EST |
| Atmospheric OH Rate Constant | 2.73E-11 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.