Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Sulfadimethoxine [USP:INN:BAN:JAN:NF]
RN: 122-11-2
UNII: 30CPC5LDEX
InChIKey: ZZORFUFYDOWNEF-UHFFFAOYSA-N

Note

  • A sulfanilamide that is used as an anti-infective agent.

Molecular Formula

  • C12-H14-N4-O4-S

Molecular Weight

  • 310.3326
 

Classification Codes

  • Anti-Infective Agents
  • Drug / Therapeutic Agent
  • Reproductive Effect
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Sulfadimethoxine
  • Sulfadimethoxine [USP:INN:BAN:JAN:NF]

MeSH Heading

  • Sulfadimethoxine

Synonyms

  • 2,4-Dimethoxy-6-sulfanilamido-1,3-diazine
  • 2,6-Dimethoxy-4-(p-aminobenzenesulfonamido)pyrimidine
  • 2,6-Dimethoxy-4-sulfanilamidopyrimidine
  • 4-Amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide
  • 4-Amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzolsulfonamid
  • 5-25-13-00290 (Beilstein Handbook Reference)
  • 6-Sulfanilamido-2,4-dimethoxypyrimidine
  • Abcid
  • Agribon
  • Albon
  • Arnosulfan
  • Bactrovet
  • BRN 0306856
  • CCRIS 9326
  • Deposul
  • Diasulfa
  • Diasulfyl
  • Dimetazina
  • Dimethoxysulfadiazine
  • Dinosol
  • Dorisul
  • EINECS 204-523-7
  • Fuxal
  • Madribon
  • Madrigid
  • Madriqid
  • Madroxin
  • Madroxine
  • Maxulvet
  • Memcozine
  • Metoxidon
  • N(sup 1)-(2,6-Dimethoxy-4-pyrimidinyl)sulfanilamide
  • N1-(2,6-Dimethoxy-4-pyrimidinyl)sulfanilamide
  • Neostrepal
  • NSC 683544
  • Omnibon
  • Persulfen
  • Radonin
  • Redifal
  • Roscosulf
  • Scandisil
  • Solfadimetossina
  • Solfadimetossina [DCIT]
  • Sudine
  • Sulfadimethoxin
  • Sulfadimethoxine
  • Sulfadimethoxinum
  • Sulfadimethoxinum [INN-Latin]
  • Sulfadimethoxydiazine
  • Sulfadimetossina
  • Sulfadimetossina [Italian]
  • Sulfadimetoxin
  • Sulfadimetoxina
  • Sulfadimetoxina [INN-Spanish]
  • SULFAMED-G
  • Sulfastop
  • Sulfoplan
  • Sulphadimethoxine
  • Sulxin
  • Symbio
  • Theracanzan
  • UNII-30CPC5LDEX

Systematic Names

  • Benzenesulfonamide, 4-amino-N-(2,6-dimethoxy-4-pyrimidinyl)-
  • Sulfadimethoxine
  • Sulfanilamide, N(sup 1)-(2,6-dimethoxy-4-pyrimidinyl)-

Mixture Names

  • Primor
  • Rofenaid

Registry Numbers

CAS Registry Number

  • 122-11-2

FDA UNII

  • 30CPC5LDEX

System Generated Number

  • 0000122112

Structure Descriptors

InChI

1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)

InChIKey

ZZORFUFYDOWNEF-UHFFFAOYSA-N

Smiles

COc1cc(nc(n1)OC)NS(=O)(=O)c2ccc(cc2)N

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral > 3200mg/kg (3200mg/kg)   Drugs in Japan Vol. 6, Pg. 386, 1982.
dog LDLo intravenous 140mg/kg (140mg/kg) VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION Chemotherapy Vol. 14, Pg. 37, 1969.
mouse LD50 intraperitoneal 866mg/kg (866mg/kg)   Drugs in Japan Vol. 6, Pg. 386, 1982.
mouse LD50 intravenous 844mg/kg (844mg/kg)   Drugs in Japan Vol. 6, Pg. 386, 1982.
mouse LD50 oral 3200mg/kg (3200mg/kg)   Drugs in Japan Vol. -, Pg. 614, 1995.
mouse LD50 subcutaneous 791mg/kg (791mg/kg)   Drugs in Japan Vol. 6, Pg. 386, 1982.
rabbit LD50 intravenous 1gm/kg (1000mg/kg)   Drugs in Japan Vol. 6, Pg. 386, 1982.
rabbit LD50 oral > 1gm/kg (1000mg/kg)   Drugs in Japan Vol. 6, Pg. 386, 1982.
rat LD unreported > 10gm/kg (10000mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 58(12), Pg. 9, 1993.
rat LDLo oral 10gm/kg (10000mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 40(9), Pg. 115, 1975.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 203.5 deg C   EXP
log P (octanol-water) 1.63 (none)   EXP
Water Solubility 343 mg/L   EXP
Vapor Pressure 1.59E-09 mm Hg 25 EST
Henry's Law Constant 1.30E-14 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 2.02E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.