Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Phenyl glycidyl ether
RN: 122-60-1
UNII: 44KJQ1655I
InChIKey: FQYUMYWMJTYZTK-UHFFFAOYSA-N

Note

  • (11 alpha,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid (PGE(1)); (5Z,11 alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (PGE(2)); and (5Z,11 alpha,13E,15S,17Z)-11,15-dihydroxy-9-oxoprosta-5,13,17-trien-1-oic acid (PGE(3)). Three of the six naturally occurring prostaglandins. They are considered primary in that no one is derived from another in living organisms. Originally isolated from sheep seminal fluid and vesicles, they are found in many organs and tissues and play a major role in mediating various physiological activities.

Molecular Formula

  • C9-H10-O2

Molecular Weight

  • 150.176
 

Classification Codes

Classification Codes

  • Mutation Data
  • Reproductive Effect
  • Skin / Eye Irritant
  • TSCA Flag T (Subject to the Section 4 Test Rule under TSCA)
  • Tumor Data

Superlist Classification Codes

  • Overall Carcinogenic Evaluation: Group 2B
  • TWA (0.1 ppm); Skin; Sensitizer; Confirmed animal carcinogen with unknown relevance to humans
  • TWA 10 ppm (60 mg/m3)
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Phenyl glycidyl ether
  • Phenylglycidyl ether

Synonyms

  • (+/-)-(2,3-Epoxypropyl)phenylether
  • (Phenoxymethyl)oxirane
  • 1,2-Epoxy-3-phenoxypropane
  • 1-Phenoxy-2,3-epoxypropane
  • 2,3-Epoxy-1-phenoxypropane
  • 2,3-Epoxypropyl phenyl ether
  • 2,3-Epoxypropylphenyl ether
  • 3-Phenoxy-1,2-epoxypropane
  • 3-Phenoxy-1,2-propylene oxide
  • 3-Phenyloxy-1,2-epoxypropane
  • 5-17-03-00013 (Beilstein Handbook Reference)
  • Ageflex PGE
  • AI3-13109
  • Benzene, (2,3-epoxypropoxy)-
  • BRN 0002744
  • CCRIS 738
  • EC 204-557-2
  • EINECS 204-557-2
  • Ether, 2,3-epoxypropyl phenyl
  • Ether, phenylglycidyl
  • Fenyl-glycidylether
  • Fenyl-glycidylether [Czech]
  • Glycidol phenyl ether
  • Glycidyl phenyl ether
  • Heloxy WC-63
  • HSDB 1821
  • NSC 53476
  • Oxirane, (phenoxymethyl)-
  • PGE
  • Phenol glycidyl ether
  • Phenol-glycidaether
  • Phenol-glycidaether [German]
  • Phenoxypropene oxide
  • Phenoxypropylene oxide
  • Phenyl 2,3-epoxypropyl ether
  • Phenyl glycidyl ether
  • Phenylglycidyl ether
  • Phenylglycydyl ether
  • Propane, 1,2-epoxy-3-phenoxy-
  • UNII-44KJQ1655I

Systematic Names

  • 2,3-Epoxypropyl phenyl ether
  • Oxirane, (phenoxymethyl)-
  • Oxirane, 2-(phenoxymethyl)-
  • Phenyl glycidyl ether
  • Propane, 1,2-epoxy-3-phenoxy-

Superlist Names

  • Oxirane, (phenoxymethyl)-
  • PGE
  • Phenyl glycidyl ether

Registry Numbers

CAS Registry Number

  • 122-60-1

FDA UNII

  • 44KJQ1655I

Other Registry Number

  • 66527-93-3

System Generated Number

  • 0000122601

Structure Descriptors

InChI

1S/C9H10O2/c1-2-4-8(5-3-1)10-6-9-7-11-9/h1-5,9H,6-7H2

InChIKey

FQYUMYWMJTYZTK-UHFFFAOYSA-N

Smiles

c1(OC[C@@H]2CO2)ccccc1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LC50 inhalation > 100ppm/4H (100ppm) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA AMA Archives of Industrial Health. Vol. 14, Pg. 250, 1956.
mouse LD50 oral 1400mg/kg (1400mg/kg) BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS

BEHAVIORAL: ATAXIA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
AMA Archives of Industrial Health. Vol. 14, Pg. 250, 1956.
mouse LD50 subcutaneous 760mg/kg (760mg/kg) AUTONOMIC NERVOUS SYSTEM: "SMOOTH MUSCLE RELAXANT (MECHANISM UNDEFINED, SPASMOLYTIC)" Arzneimittel-Forschung. Drug Research. Vol. 15, Pg. 1355, 1965.
rabbit LD50 skin 1500uL/kg (1.5mL/kg)   AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 10, Pg. 61, 1954.
rat LC50 inhalation > 100ppm/8H (100ppm) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA AMA Archives of Industrial Health. Vol. 14, Pg. 250, 1956.
rat LD50 oral 3850mg/kg (3850mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ATAXIA

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
AMA Archives of Industrial Health. Vol. 14, Pg. 250, 1956.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 3.5 deg C   EXP
Boiling Point 243 deg C   EXP
log P (octanol-water) 1.610 (none)   EST
Water Solubility 2400 mg/L 25 EXP
Vapor Pressure 0.01 mm Hg 25 EXP
Henry's Law Constant 8.23E-07 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 2.90E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.