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Substance Name: Rosiglitazone [INN:BAN]
RN: 122320-73-4
UNII: 05V02F2KDG
InChIKey: YASAKCUCGLMORW-UHFFFAOYSA-N

Note

  • A thiazolidinedione that functions as a selective agonist for PPAR GAMMA. It improves INSULIN SENSITIVITY in adipose tissue, skeletal muscle, and the liver of patients with TYPE 2 DIABETES MELLITUS.

Molecular Formula

  • C18-H19-N3-O3-S

Molecular Weight

  • 357.4321
 

Classification Code

  • Hypoglycemic Agents

Names and Synonyms

Name of Substance

  • Rosiglitazone
  • Rosiglitazone [INN:BAN]

MeSH Heading

  • Rosiglitazone

Synonyms

  • 5-((4-(2-Methyl-2-(pyridinylamino)ethoxy)phenyl)methyl)-2,4-thiazolidinedione-2-butenedioate
  • BRL 49653
  • BRL-49653
  • BRL49653
  • HSDB 7555
  • NSC 758698
  • Rosiglitazone
  • TDZ 01
  • UNII-05V02F2KDG

Systematic Name

  • 2,4-Thiazolidinedione, 5-((4-(2-(methyl-2-pyridinylamino)ethoxy)phenyl)methyl)-

Registry Numbers

CAS Registry Number

  • 122320-73-4

FDA UNII

  • 05V02F2KDG

System Generated Number

  • 0122320734

Structure Descriptors

InChI

InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,15H,10-12H2,1H3,(H,20,22,23)

InChIKey

YASAKCUCGLMORW-UHFFFAOYSA-N

Smiles

CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)c3ccccn3