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Substance Name: Sun 5555
RN: 122547-49-3
UNII: 7O46G914RQ
InChIKey: ICSAXRANXQSPQP-VUKDEKJYSA-M

Classification Codes

  • Drug / Therapeutic Agent
  • Reproductive Effect

Molecular Formula

  • C12-H15-N-O5-S.Na

Molecular Weight

  • 307.3006
 
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Names and Synonyms

Name of Substance

  • SUN 5555

Synonyms

  • (5R,6S)-6-(1(R)-Hydroxyethyl)-2-(2(R)-tetrahydrofuryl)penem-3-carboxylic acid monosodium salt
  • ALP 201
  • CCRIS 6723
  • Fropenum sodium
  • SUN 5555
  • SY5555
  • UNII-7O46G914RQ
  • YM-044

Systematic Names

  • 4-Thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-7-oxo-3-(tetrahydro-2-furanyl)-, monosodium salt, (5R-(3(R*),5-alpha,6-alpha(R*)))-
  • Fropenem sodium

Registry Numbers

CAS Registry Number

  • 122547-49-3

FDA UNII

  • 7O46G914RQ

System Generated Number

  • 0122547493

Molecular Formulas

Molecular Formula

  • C12-H15-N-O5-S.Na

Molecular Formula Fragments

  • C12-H15-N-O5-S
  • COMPONENT
  • Na

Structure Descriptors

InChI

1S/C12H15NO5S.Na/c1-5(14)7-10(15)13-8(12(16)17)9(19-11(7)13)6-3-2-4-18-6;/h5-7,11,14H,2-4H2,1H3,(H,16,17);/q;+1/p-1/t5-,6-,7+,11-;/m1./s1

InChIKey

ICSAXRANXQSPQP-VUKDEKJYSA-M

Smiles

C[C@H]([C@@H]1[C@@H]2N(C1=O)C(=C(S2)[C@H]3CCCO3)C(=O)[O-])O.[Na+]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD oral > 3gm/kg (3000mg/kg)   Chemotherapy Vol. 42(Suppl,
dog LD50 intravenous > 1200mg/kg (1200mg/kg)   Drugs of the Future. Vol. 18, Pg. 525, 1993.
mouse LD50 intravenous 3300mg/kg (3300mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

KIDNEY, URETER, AND BLADDER: INCONTINENCE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Chemotherapy Vol. 42(Suppl,
mouse LD50 oral > 2gm/kg (2000mg/kg)   Drugs of the Future. Vol. 18, Pg. 525, 1993.
rat LD50 oral > 2gm/kg (2000mg/kg)   Drugs of the Future. Vol. 18, Pg. 525, 1993.
rat LDLo intravenous 800mg/kg (800mg/kg) KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"

KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 25, Pg. 1781, 1997.