Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Mefexamide [USAN:INN]
RN: 1227-61-8
UNII: 84FP054Z2Q
InChIKey: HUNIPYLVUPMFCZ-UHFFFAOYSA-N

Note

  • Proposed psychotherapeutic agent with stimulatory action.

Classification Codes

  • Drug / Therapeutic Agent
  • Stimulant (Central)

Molecular Formula

  • C15-H24-N2-O3

Molecular Weight

  • 280.3656
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Mefexamide
  • Mefexamide [USAN:INN]

Synonyms

  • 2-(p-Methoxyphenoxy)-N-(2-(diethylamino)ethyl)acetamide
  • Acetamide, N-(2-(diethylamino)ethyl)-2-(4-methoxyphenoxy)-
  • ANP 297
  • BRN 2219009
  • EINECS 214-963-1
  • Mefaxadyne
  • Mefesamide
  • Mefesamide [DCIT]
  • Mefexadyne
  • Mefexamida
  • Mefexamida [INN-Spanish]
  • Mefexamide
  • Mefexamidum
  • Mefexamidum [INN-Latin]
  • Mephexamide
  • Mexephenamide
  • N-(2-(Diethylamino)ethyl)-2-(p-methoxyphenoxy)acetamide
  • Timodyne
  • U-25701A
  • UNII-84FP054Z2Q

Systematic Names

  • Acetamide, N-(2-(diethylamino)ethyl)-2-(4-methoxyphenoxy)-
  • Acetamide, N-(2-(diethylamino)ethyl)-2-(p-methoxyphenoxy)-
  • Mefexamide

Registry Numbers

CAS Registry Number

  • 1227-61-8

FDA UNII

  • 84FP054Z2Q

Related Registry Number

  • 3413-64-7 (mono-hydrochloride)

System Generated Number

  • 0001227618

Structure Descriptors

InChI

1S/C15H24N2O3/c1-4-17(5-2)11-10-16-15(18)12-20-14-8-6-13(19-3)7-9-14/h6-9H,4-5,10-12H2,1-3H3,(H,16,18)

InChIKey

HUNIPYLVUPMFCZ-UHFFFAOYSA-N

Smiles

CCN(CC)CCNC(=O)COc1ccc(cc1)OC

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 110mg/kg (110mg/kg)   French Medicament Patent Document. Vol. #2702M,
mouse LD50 oral 1500ug/kg (1.5mg/kg)   Chimica Therapeutica. Vol. 1, Pg. 444, 1966.
rabbit LD50 intravenous 135mg/kg (135mg/kg)   Annales Medico-Psychologiques. Vol. 123, Pg. 141, 1965.

Physical Properties

Physical Property Value Units Temp (deg C) Source
log P (octanol-water) 1.790 (none)   EST
Atmospheric OH Rate Constant 1.28E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.