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Substance Name: 4-Aminophenol
RN: 123-30-8
UNII: R7P8FRP05V
InChIKey: PLIKAWJENQZMHA-UHFFFAOYSA-N

Classification Codes

  • Mutagens
  • Mutation Data
  • Noxae
  • Reproductive Effect
  • Skin / Eye Irritant
  • TSCA Flag TP (Subject to the Proposed TSCA Section 4 Test Rule)

Molecular Formula

  • C6-H7-N-O

Molecular Weight

  • 109.127
 

Names and Synonyms

Name of Substance

  • 4-Aminophenol
  • CI 76550
  • p-Aminophenol
  • Phenol, 4-amino-

Synonyms

  • 1-Amino-4-hydroxybenzene
  • 4-Amino-1-hydroxybenzene
  • 4-Aminophenol
  • 4-Hydroxyaniline
  • Activol
  • AI3-14872
  • Azol
  • BASF Ursol P Base
  • Benzofur P
  • C.I. 76550
  • C.I. Oxidation Base 6
  • CCRIS 4146
  • Certinal
  • CI 76550
  • Citol
  • Durafur Brown RB
  • EC 204-616-2
  • EINECS 204-616-2
  • Fouramine P
  • Fourrine 84
  • Fourrine P Base
  • Furro P Base
  • HSDB 2640
  • Nako Brown R
  • NSC 1545
  • p-Aminofenol
  • p-Aminofenol [Czech]
  • p-Aminophenol
  • p-Hydroxyaniline
  • p-Hydroxyphenylamine
  • PAP
  • Paranol
  • Pelagol Grey P Base
  • Pelagol P Base
  • Renal AC
  • Rodinal
  • Tertral P base
  • Unal
  • UNII-R7P8FRP05V
  • Ursol P
  • Ursol P base
  • Zoba Brown P Base

Systematic Names

  • 4-Aminophenol
  • p-Aminophenol
  • Phenol, 4-amino-
  • Phenol, p-amino-

Superlist Names

  • Aminophenol, p-
  • p-Aminophenol
  • p-Aminophenol [UN2512] [Poison]
  • Phenol, p-amino-
  • UN2512

Registry Numbers

CAS Registry Number

  • 123-30-8

FDA UNII

  • R7P8FRP05V

Other Registry Numbers

  • 1309774-68-2
  • 52985-09-8

Related Registry Numbers

  • 51-78-5 (hydrochloride)
  • 63084-98-0 (sulfate [2:1])

System Generated Number

  • 0000123308

Structure Descriptors

InChI

1S/C6H7NO/c7-5-1-3-6(8)4-2-5/h1-4,8H,7H2

InChIKey

PLIKAWJENQZMHA-UHFFFAOYSA-N

Smiles

c1(ccc(O)cc1)N

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LD50 oral 56200ug/kg (56.2mg/kg)   Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
cat LDLo subcutaneous 37mg/kg (37mg/kg)   Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 72, Pg. 241, 1913.
cat LDLo subcutaneous 37mg/kg (37mg/kg) BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN

LUNGS, THORAX, OR RESPIRATION: CYANOSIS
Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 72, Pg. 241, 1913.
guinea pig LDLo subcutaneous 1500mg/kg (1500mg/kg)   Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 35, Pg. 401, 1895.
mammal (species unspecified) LD50 oral 1530mg/kg (1530mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(10), Pg. 16, 1980.
mammal (species unspecified) LD50 skin 6400mg/kg (6400mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(10), Pg. 16, 1980.
mammal (species unspecified) LD50 unreported 563mg/kg (563mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 48(9), Pg. 19, 1983.
mouse LD50 unreported 750mg/kg (750mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 50(3), Pg. 4, 1985.
mouse LDLo intraperitoneal 100mg/kg (100mg/kg)   Revue Belge de Pathologie et de Medecine Experimentale. Vol. 22, Pg. 1, 1952.
mouse LDLo subcutaneous 470mg/kg (470mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 188, Pg. 130, 1938.
rabbit LD50 oral 10gm/kg (10000mg/kg)   Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 52, Pg. 215, 1956.
rabbit LD50 skin > 10gm/kg (10000mg/kg)   BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 29-4/1973,
rat LC50 inhalation > 5mg/m3/1H (5mg/m3)   BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 29-4/1973,
rat LD50 intraperitoneal 465mg/kg (465mg/kg) BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN Journal of Pharmacology and Experimental Therapeutics. Vol. 80, Pg. 31, 1944.
rat LD50 oral 375mg/kg (375mg/kg)   BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 29-4/1973,
rat LD50 oral 375mg/kg (375mg/kg) LUNGS, THORAX, OR RESPIRATION: CYANOSIS

BEHAVIORAL: MUSCLE WEAKNESS
BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 29-4/1973,
rat LD50 unreported 675mg/kg (675mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 50(3), Pg. 4, 1985.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 187.5 deg C   EXP
Boiling Point 284 deg C   EXP
pKa Dissociation Constant 5.48 (none)   EXP
log P (octanol-water) 0.04 (none)   EXP
Water Solubility 1.60E+04 mg/L 20 EXP
Henry's Law Constant 3.59E-10 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 7.42E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.