Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Clazakizumab [USAN:INN]
RN: 1236278-28-6
UNII: 4S38Z8RA9O

Notes

  • A humanized monoclonal antibody specific for interleukin-6 (IL-6).
  • Targets interleukin-6; in phase 2 clinical trials (2013).

Molecular Formula

  • C6426-H9972-N1724-O2032-S42
 

Classification Code

  • Autoimmune Diseases, Rheumatoid Arthritis
* denotes mobile formatted website

Links to Resources

Names and Synonyms

Name of Substance

  • Clazakizumab [USAN:INN]

Synonyms

  • ALD 518
  • ALD518
  • BMS 945429
  • BMS-945429
  • Clazakizumab
  • Immunoglobulin G1, anti-(human interleukin-6 (B-cell stimulatory factor 2, CTL differentiation factor, hybridoma growth factor, interferon beta-2)); humanized rabbit monoclonal BMS-945429/ALD518 (300-alanine(CH2-N(sup 67)>A(sup 67)))gamma1 heavy chain (223-217')-disulfide with humanized rabbit monoclonal BMS-945429/ALD518 kappa light chain dimer (229-229'':232-232'')-bisdisulfide, O-glycosylated
  • UNII-4S38Z8RA9O

Systematic Name

  • Immunoglobulin G1, anti-(human interleukin 6) (human-Oryctolagus cuniculus monoclonal BMS-945429/ALD518 heavy chain), disulfide with human-Oryctolagus cuniculus monoclonal BMS-945429/ALD518 kappa-chain, dimer

Registry Numbers

CAS Registry Number

  • 1236278-28-6

FDA UNII

  • 4S38Z8RA9O

System Generated Number

  • 1236278286