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Substance Name: Furazabol [INN:JAN]
RN: 1239-29-8
UNII: 2W07HSP5PX
InChIKey: RGLLOUBXMOGLDQ-IVEVATEUSA-N

Classification Codes

  • Drug / Therapeutic Agent
  • Reproductive Effect

Molecular Formula

  • C20-H30-N2-O2

Molecular Weight

  • 330.469
 
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Names and Synonyms

Name of Substance

  • Furazabol
  • Furazabol [INN:JAN]

Synonyms

  • 17-beta-Hydroxy-17-alpha-methyl-5-alpha-androstano(2,3-c)furazan
  • 17-Methyl-5-alpha-androstano(2,3-c)(1,2,5)oxadiazol-17-beta-ol
  • 17-Methyl-5alpha-androstano(2,3-c)furazan-17beta-ol
  • Androfurazanol
  • DH 245
  • EINECS 214-983-0
  • Frazalon
  • Furazabol
  • Furazabolo
  • Furazabolo [DCIT]
  • Furazabolum
  • Furazabolum [INN-Latin]
  • Miotolon
  • Myotolon
  • Qu Zhi Shu
  • UNII-2W07HSP5PX

Systematic Names

  • 17-Methyl-5alpha-androstano(2,3-c)(1,2,5)oxadiazol-17beta-ol
  • 17-Methyl-5alpha-androstano(2,3-c)furazan-17beta-ol
  • 5-alpha-Androstano(2,3-c)(1,2,5)oxadiazol-17-beta-ol, 17-methyl-
  • Furazabol

Superlist Names

  • 17alpha-Methyl-17beta-hydroxyandrostano(2,3-c)-furazan
  • DEA No. 4000
  • Furazabol

Registry Numbers

CAS Registry Number

  • 1239-29-8

FDA UNII

  • 2W07HSP5PX

System Generated Number

  • 0001239298

Structure Descriptors

InChI

1S/C20H30N2O2/c1-18-11-17-16(21-24-22-17)10-12(18)4-5-13-14(18)6-8-19(2)15(13)7-9-20(19,3)23/h12-15,23H,4-11H2,1-3H3/t12-,13+,14-,15-,18-,19-,20-/m0/s1

InChIKey

RGLLOUBXMOGLDQ-IVEVATEUSA-N

Smiles

C[C@]1(O)CC[C@H]2[C@@H]3CC[C@H]4Cc5nonc5C[C@]4(C)[C@H]3CC[C@]12C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 494mg/kg (494mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
Chemical and Pharmaceutical Bulletin. Vol. 14, Pg. 285, 1966.
mouse LD50 oral 1731mg/kg (1731mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 3, Pg. 187, 1969.
mouse LD50 subcutaneous > 4gm/kg (4000mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Chemical and Pharmaceutical Bulletin. Vol. 14, Pg. 285, 1966.
rat LD50 intraperitoneal 745mg/kg (745mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 2031, 1970.
rat LD50 oral > 4gm/kg (4000mg/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM DUODENUM
Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 2031, 1970.
rat LD50 subcutaneous > 4gm/kg (4000mg/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM DUODENUM
Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 2031, 1970.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 152.5 deg C   EXP
log P (octanol-water) 3.980 (none)   EST
Atmospheric OH Rate Constant 2.98E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.