Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Dynemicin A
RN: 124412-57-3
UNII: D3G8N2863A
InChIKey: AFMYMMXSQGUCBK-ARJAWSKDSA-N

Note

  • Isolated from Micromonospora.

Molecular Formula

  • C30-H19-N-O9

Molecular Weight

  • 537.478
 

Classification Codes

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antibiotics, Antineoplastic
  • Antineoplastic Agents
  • Drug / Therapeutic Agent
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Dynemicin A

Synonyms

  • BRN 5469129
  • BU-3420T
  • Dynemicin A
  • UNII-D3G8N2863A

Systematic Names

  • 4a,14a-Epoxy-4,14-(3)hexene(1,5)diynonaphtho(2,3-c)phenanthridine-2-carboxylic acid, 1,4,7,12,13,14-hexahydro-6,8,11-trihydroxy-3-methoxy-1-methyl-7,12-dioxo-, (1S,4R,4aR,14S,14aS,18Z)-
  • 4a,14a-Epoxy-4,14-(3)hexene(1,5)diynonaphtho(2,3-c)phenanthridine-2-carboxylic acid, 1,4,7,12,13,14-hexahydro-7,12-dioxo-3-methoxy-1-methyl-6,8,11-trihydroxy-, (1S-(1R*,4S*,4aS*,14R*,14aR*))-

Registry Numbers

CAS Registry Number

  • 124412-57-3

FDA UNII

  • D3G8N2863A

System Generated Number

  • 0124412573

Structure Descriptors

InChI

1S/C30H19NO9/c1-12-19(28(37)38)27(39-2)13-7-5-3-4-6-8-18-29(12)30(13,40-29)14-11-17(34)22-23(24(14)31-18)26(36)21-16(33)10-9-15(32)20(21)25(22)35/h3-4,9-13,18,31-34H,1-2H3,(H,37,38)/b4-3-

InChIKey

AFMYMMXSQGUCBK-ARJAWSKDSA-N

Smiles

c1c(c2c(c(O)c1)C(=O)c1c(C2=O)c2c(cc1O)[C@@]13[C@@H]4C(=C([C@@H]([C@@]1(O3)[C@@H](C#CC=CC#C4)N2)C)C(=O)O)OC)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD intramuscular > 5mg/kg (5mg/kg)   United States Patent Document. Vol. #5116845,
mouse LD50 intraperitoneal 580ug/kg (0.58mg/kg)   Journal of Antibiotics. Vol. 44, Pg. 1306, 1991.