Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Losartan carboxylic acid
RN: 124750-92-1
UNII: GD76OCH73X
InChIKey: ZEUXAIYYDDCIRX-UHFFFAOYSA-N

Classification Codes

  • Anti-Arrhythmia Agents
  • Antihypertensive Agents
  • Cardiovascular Agents
  • Drug / Therapeutic Agent

Molecular Formula

  • C22-H21-Cl-N6-O2

Molecular Weight

  • 436.9009
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Losartan carboxylic acid

Synonyms

  • E-3174
  • EXP 3174
  • EXP-3174
  • L 158641
  • L-158641
  • UNII-GD76OCH73X

Systematic Name

  • 1H-Imidazole-5-carboxylic acid, 2-butyl-4-chloro-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-

Registry Numbers

CAS Registry Number

  • 124750-92-1

FDA UNII

  • GD76OCH73X

System Generated Number

  • 0124750921

Structure Descriptors

InChI

1S/C22H21ClN6O2/c1-2-3-8-18-24-20(23)19(22(30)31)29(18)13-14-9-11-15(12-10-14)16-6-4-5-7-17(16)21-25-27-28-26-21/h4-7,9-12H,2-3,8,13H2,1H3,(H,30,31)(H,25,26,27,28)

InChIKey

ZEUXAIYYDDCIRX-UHFFFAOYSA-N

Smiles

CCCCc1nc(c(n1Cc2ccc(cc2)c3ccccc3c4[nH]nnn4)C(=O)O)Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 441mg/kg (441mg/kg) SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: TREMOR
Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.