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Substance Name: Valacyclovir hydrochloride [USAN:USP]
RN: 124832-27-5
UNII: G447S0T1VC
InChIKey: ZCDDBUOENGJMLV-QRPNPIFTSA-N

Note

  • A prodrug of acyclovir; 53% of oral dose excreted as acyclovir in the urine; a 200-400% improvement on acyclovir; used in the management of HSV and VZV infections and the prophylaxis of HCMV infections.

Molecular Formula

  • C13-H20-N6-O4.Cl-H

Molecular Weight

  • 360.7999
 

Classification Codes

  • Anti-Infective Agents
  • Antiviral
  • Antiviral Agents

Names and Synonyms

Name of Substance

  • Valacyclovir
  • Valacyclovir hydrochloride
  • Valacyclovir hydrochloride [USAN:USP]

Synonyms

  • 256U87 hydrochloride
  • BW 256
  • BW-256U87
  • L-Valine, 2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)ethyl ester, monohydrochloride
  • L-Valine, ester with 9-((2-hydroxyethoxy)methyl)guanine, monohydrochloride
  • UNII-G447S0T1VC
  • Valaciclovir hydrochloride
  • Valacyclovir
  • Valacyclovir HCl
  • Valacyclovir hydrochloride
  • Valtrex
  • Zelitrex

Systematic Name

  • L-Valine, 2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)ethyl ester, monohydrochloride

Registry Numbers

CAS Registry Number

  • 124832-27-5

FDA UNII

  • G447S0T1VC

Other Registry Number

  • 136489-37-7

System Generated Number

  • 0124832275

Molecular Formulas

Molecular Formula

  • C13-H20-N6-O4.Cl-H

Molecular Formula Fragments

  • C13-H20-N6-O4
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

InChI=1S/C13H20N6O4.ClH/c1-7(2)8(14)12(21)23-4-3-22-6-19-5-16-9-10(19)17-13(15)18-11(9)20;/h5,7-8H,3-4,6,14H2,1-2H3,(H3,15,17,18,20);1H/t8-;/m0./s1

InChIKey

ZCDDBUOENGJMLV-QRPNPIFTSA-N

Smiles

Cl.CC(C)[C@H](N)C(=O)OCCOCn1cnc2C(=O)N=C(N)Nc12