Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Hydrocortisone sodium succinate [USP:BAN:JAN]
RN: 125-04-2
UNII: 50LQB69S1Z
InChIKey: HHZQLQREDATOBM-CODXZCKSSA-M

Classification Codes

  • Drug / Therapeutic Agent
  • Glucocorticoid
  • Human Data
  • Reproductive Effect

Molecular Formulas

  • C25-H33-Na-O8
  • C25-H34-O8.Na

Molecular Weight

  • 484.5177
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Cortisol succinate
  • Hydrocortisone sodium succinate [USP:BAN:JAN]

Synonyms

  • A-hydroCort
  • Arcocort
  • Buccalsone
  • Corlan
  • Cortisol 21-(sodium succinate)
  • Cortisol hemisuccinate sodium salt
  • Cortisol sodium hemisuccinate
  • Cortisol sodium succinate
  • Cortop
  • EF-Cortelan soluble
  • EINECS 204-725-5
  • Emi-Corlin
  • Flebocortid
  • Flebocortid [inj.]
  • Hidrokortizon
  • Hycorace
  • Hydro-Adreson aquosum
  • Hydrocort
  • Hydrocortisone 21-hemisuccinate sodium salt
  • Hydrocortisone 21-sodium succinate
  • Hydrocortisone 21-sodium succinide
  • Hydrocortisone 21-succinate sodium salt
  • Hydrocortisone hemisuccinate
  • Hydrocortisone hemisuccinate sodium salt
  • Hydrocortisone sodium 21-hemisuccinate
  • Hydrocortisone sodium hemisuccinate
  • Hydrocortisone sodium succinate
  • Hydrocortisone succinate,sodium salt
  • Hydrocortisone-21-hemisuccinate sodium
  • Hydrocortisone-21-hemisuccinate sodium salt
  • Idrocortisone B. I. L.
  • Intracort
  • Lycortin-S
  • Nordicort
  • Nositrol
  • NSC 9152
  • Oralsone
  • Rapicort
  • Sodium 17-hydroxycorticosterone 21-succinate
  • Sodium hydrocortisone 21-hemisuccinate
  • Sodium hydrocortisone 21-succinate
  • Sodium hydrocortisone succinate
  • Solu-Cortef
  • Solu-Glyc
  • Solu-Hizon
  • U 4905
  • UNII-50LQB69S1Z

Systematic Names

  • Cortisol, 21-(hydrogen succinate), monosodium salt (8CI)
  • Cortisol, succinate, sodium salt
  • Hydrocortisone 21-(sodium succinate)
  • Pregn-4-ene-3,20-dione, 21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-, monosodium salt, (11beta)-

Registry Numbers

CAS Registry Number

  • 125-04-2

FDA UNII

  • 50LQB69S1Z

Related Registry Number

  • 2203-97-6 (Parent)

System Generated Number

  • 0000125042

Molecular Formulas

Molecular Formulas

  • C25-H33-Na-O8
  • C25-H34-O8.Na

Molecular Formula Fragments

  • C25-H34-O8
  • COMPONENT
  • Na

Structure Descriptors

InChI

1S/C25H34O8.Na/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30;/h11,16-18,22,27,32H,3-10,12-13H2,1-2H3,(H,29,30);/q;+1/p-1/t16-,17-,18-,22+,23-,24-,25-;/m0./s1

InChIKey

HHZQLQREDATOBM-CODXZCKSSA-M

Smiles

[C@@]12([C@H]([C@H]3[C@H]([C@H](C2)O)[C@@]2(C(=CC(=O)CC2)CC3)C)CC[C@@]1(C(=O)COC(=O)CCC(=O)[O-])O)C.[Na+]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man LDLo intravenous 1429ug/kg (1.429mg/kg) CARDIAC: OTHER CHANGES

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Medical Journal of Australia. Vol. 154, Pg. 782, 1991.
man TDLo intravenous 2857ug/kg (2.857mg/kg) BLOOD: OXIDANT RELATED (GPD DEFICIENT) ANEMIA

GASTROINTESTINAL: NAUSEA OR VOMITING

LUNGS, THORAX, OR RESPIRATION: BRONCHIOLAR CONSTRICTION
Medical Journal of Australia. Vol. 154, Pg. 210, 1991.
mouse LD50 intraperitoneal 1050mg/kg (1050mg/kg)   Drugs in Japan Vol. 6, Pg. 625, 1982.
rat LD50 intraperitoneal 1320mg/kg (1320mg/kg)   Drugs in Japan Vol. 6, Pg. 625, 1982.