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Substance Name: Hydrocodone [INN:BAN]
RN: 125-29-1
UNII: 6YKS4Y3WQ7
InChIKey: LLPOLZWFYMWNKH-CMKMFDCUSA-N
Note
- Narcotic analgesic related to CODEINE, but more potent and more addicting by weight. It is used also as cough suppressant.
Molecular Formula
- C18-H21-N-O3
Molecular Weight
- 299.3679
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
Classification Codes
- Analgesics
- Analgesics, Opioid
- Antitussive Agents
- Central Nervous System Agents
- Central Nervous System Depressants
- Drug / Therapeutic Agent
- Narcotics
- Peripheral Nervous System Agents
- Respiratory System Agents
- Sensory System Agents
Superlist Classification Code
- DEA Schedule II
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Links to Resources
NLM Resources (File Locators)
Regulatory Agencies (Superlist Locators)
Other Resources (Internet Locators)
Search for this InChIKey on the Web
Names and Synonyms
Results Name
- Hydrocodone [INN:BAN]
Name of Substance
- Hydrocodone
- Hydrocodone polistirex [USAN]
- Hydrocodone [INN:BAN]
MeSH Heading
- Hydrocodone
Synonyms
- (-)-Dihydrocodeinone
- 4,5-alpha-Epoxy-3-methoxy-17-methylmorphinan-6-one
- 4,5alpha-Epoxy-3-methoxy-17-methylmorphinan-6-one
- 4-27-00-03580 (Beilstein Handbook Reference)
- 6-Oxo-3-methoxy-N-methyl-4,5-epoxymorphinan
- Bekadid
- BRN 0094193
- Codeinone, dihydro-
- Codinovo
- DICO
- Dicodid
- Dihydrocodeinone
- EINECS 204-733-9
- Hidrocodona
- Hidrocodona [INN-Spanish]
- HSDB 3097
- Hydrocodon
- Hydrocodone
- Hydrocodone polistirex
- Hydrocodonum
- Hydrocodonum [INN-Latin]
- Hydrocone
- Hydroconum
- Idrocodone
- Idrocodone [DCIT]
- Multacodin
- NSC 19044
- UNII-6YKS4Y3WQ7
Systematic Names
- Hydrocodone
- Morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl-
- Morphinan-6-one, 4,5-epoxy-3-methoxy-17-methyl-, (5alpha)- (9CI)
- Morphinan-6-one, 4,5alpha-epoxy-3-methoxy-17-methyl- (8CI)
Superlist Names
- DEA No. 9193
- Hydrocodone
Registry Numbers
CAS Registry Number
- 125-29-1
FDA UNII
- 6YKS4Y3WQ7
Other Registry Numbers
- 1037-91-8
- 1469752-80-4
- 50678-79-0
- 9007-52-7
Related Registry Number
- 34195-34-1 (tartrate (1:1), hydrate (2:5))
System Generated Number
- 0000125291
Structure Descriptors
InChI
1S/C18H21NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3,6,11-12,17H,4-5,7-9H2,1-2H3/t11-,12+,17-,18-/m0/s1InChIKey
LLPOLZWFYMWNKH-CMKMFDCUSA-NSmiles
COc1ccc2C[C@@H]3[C@@H]4CCC(=O)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cat | LDLo | intravenous | 9mg/kg (9mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: ANALGESIA | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 194, Pg. 296, 1940. |
mouse | LD50 | subcutaneous | 86mg/kg (86mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of Pharmacology and Experimental Therapeutics. Vol. 52, Pg. 468, 1934. |
rabbit | LDLo | intravenous | 7mg/kg (7mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: ANALGESIA | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 194, Pg. 296, 1940. |
rat | LD50 | subcutaneous | 150mg/kg (150mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 238, 1953. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 198 | deg C | EXP | |
log P (octanol-water) | 2.160 | (none) | EST | |
Water Solubility | 6870 | mg/L | 25 | EST |
Vapor Pressure | 2.83E-07 | mm Hg | 25 | EST |
Henry's Law Constant | 6.37E-12 | atm-m3/mole | 25 | EST |
Atmospheric OH Rate Constant | 1.80E-10 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.