Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: GP 7
RN: 125670-69-1
InChIKey: MNYFRPDQBQTHSV-IWRQBJDLSA-N

Classification Codes

  • Drug / Therapeutic Agent
  • Mutation Data

Molecular Formula

  • C30-H37-N2-O8

Molecular Weight

  • 553.6283
 
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • GP 7

Synonyms

  • 4-(2,2,6,6-Tetramethyl-1-oxylpiperidin-4-ylamino)-4'-demethylepipodophyllotoxin
  • 4-(4''-(2'',2'',6'',6''-Tetramethyl-1''-piperidinyloxy)amino)-4'-demethylepipodophyllotoxin
  • GP 7
  • GP-7,3

Systematic Name

  • 1-Piperidinyloxy, 4-((5,5a,6,8,8a,9-hexahydro-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxofuro(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-5-yl)amino)-2,2,6,6-tetramethyl-, (5-alpha,5a-beta,8a-alpha,9-beta)-

Registry Numbers

CAS Registry Number

  • 125670-69-1

System Generated Number

  • 0125670691

Structure Descriptors

InChI

1S/C30H37N2O8/c1-29(2)11-16(12-30(3,4)32(29)35)31-26-18-10-21-20(39-14-40-21)9-17(18)24(25-19(26)13-38-28(25)34)15-7-22(36-5)27(33)23(8-15)37-6/h7-10,16,19,24-26,31,33H,11-14H2,1-6H3/t19-,24+,25-,26+/m1/s1

InChIKey

MNYFRPDQBQTHSV-IWRQBJDLSA-N

Smiles

CC1(CC(CC(N1[O])(C)C)N[C@H]2c3cc4c(cc3[C@@H]([C@H]5[C@H]2COC5=O)c6cc(c(c(c6)OC)O)OC)OCO4)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 231mg/kg (231mg/kg)   Life Sciences. Vol. 45, Pg. 2569, 1989.
mouse LD50 intravenous 231mg/kg (231mg/kg)   Drugs of the Future. Vol. 17, Pg. 191, 1992.