Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Thiopeptin
RN: 12609-84-6
InChIKey: SRTDKHGZQCTGBY-RVDKCFQWSA-N

Classification Codes

  • Drug / Therapeutic Agent
  • Natural Product

Molecular Weight

  • 1530.8391
 
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Thiopeptin

Systematic Name

  • Thiopeptin

Registry Numbers

CAS Registry Number

  • 12609-84-6

System Generated Number

  • 0012609846

Structure Descriptors

InChI

1S/C65H79N17O15S6/c1-12-33-58-76-39(20-100-58)54(92)81-48(64(11,96)30(10)85)61-77-41(22-102-61)57(98)80-44-29(9)97-62(95)36-17-32(27(7)83)31-13-14-34(46(86)45(31)71-36)70-42(23(2)3)55(93)69-25(5)51(89)67-24(4)50(88)68-26(6)52(90)82-65(63-78-40(21-103-63)53(91)79-43(28(8)84)56(94)73-33)16-15-35(59-75-38(19-99-59)49(66)87)72-47(65)37-18-101-60(44)74-37/h12-14,17-19,21-23,25-30,34-35,39,42-44,46-48,70,72,83-86,96H,4,15-16,20H2,1-3,5-11H3,(H2,66,87)(H,67,89)(H,68,88)(H,69,93)(H,73,94)(H,79,91)(H,80,98)(H,81,92)(H,82,90)/b33-12+

InChIKey

SRTDKHGZQCTGBY-RVDKCFQWSA-N

Smiles

C/C=C/1\C2=NC(CS2)C(=O)NC(c3nc(cs3)C(=S)NC4c5nc(cs5)C6C(CCC(N6)c7nc(cs7)C(=O)N)(c8nc(cs8)C(=O)NC(C(=O)N1)C(C)O)NC(=O)C(NC(=O)C(=C)NC(=O)C(NC(=O)C(NC9C=Cc1c(cc(nc1C9O)C(=O)OC4C)C(C)O)C(C)C)C)C)C(C)(C(C)O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 662mg/kg (662mg/kg)   Antimicrobial Agents and Chemotherapy. Vol. 1, Pg. 496, 1972.
mouse LD50 oral > 8gm/kg (8000mg/kg)   Antimicrobial Agents and Chemotherapy. Vol. 1, Pg. 496, 1972.
mouse LD50 subcutaneous > 5600mg/kg (5600mg/kg)   Antimicrobial Agents and Chemotherapy. Vol. 1, Pg. 496, 1972.
rat LD50 intraperitoneal 440mg/kg (440mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

GASTROINTESTINAL: RELAXATION (ISOLATED TISSUE)
Antimicrobial Agents and Chemotherapy. Vol. 1, Pg. 496, 1972.
rat LD50 oral > 4gm/kg (4000mg/kg)   Antimicrobial Agents and Chemotherapy. Vol. 1, Pg. 496, 1972.
rat LD50 subcutaneous > 2gm/kg (2000mg/kg)   Antimicrobial Agents and Chemotherapy. Vol. 1, Pg. 496, 1972.