Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Fumitremorgin B
RN: 12626-17-4
UNII: ITN5B384F8
InChIKey: WEIYXEFMCIRZHC-MWGWWEMPSA-N

Note

  • Intermediary in TR-2 mycotoxin biosyn.

Classification Code

  • Mutation Data

Molecular Formula

  • C27-H33-N3-O5

Molecular Weight

  • 479.574
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Fumitremorgin B

Synonyms

  • Fumitremorgin B
  • Lanosulin
  • UNII-ITN5B384F8

Systematic Names

  • 5H,14H-Pyrrolo(1'',2'':4',5')pyrazino(1',2':1,6)pyrido(3,4-b)indole-5,14-dione, 1,2,3,5a,6,11,12,14a-octahydro-5a,6-dihydroxy-9-methoxy-11-(3-methyl-2-butenyl)-12-(2-methyl-1-propenyl)-, (5aR,6S,12S,14aS)-
  • 5H,14H-Pyrrolo(1'',2'':4',5')pyrazino(1',2':1,6)pyrido(3,4-b)indole-5,14-dione, 1,2,3,5a,6,11,12,14a-octahydro-5a,6-dihydroxy-9-methoxy-11-(3-methyl-2-butenyl)-12-(2-methyl-1-propenyl)-, (5aR-(5a-alpha,6-alpha,12-beta,14a-alpha))-

Registry Numbers

CAS Registry Number

  • 12626-17-4

FDA UNII

  • ITN5B384F8

System Generated Number

  • 0012626174

Structure Descriptors

InChI

1S/C27H33N3O5/c1-15(2)10-12-28-20-14-17(35-5)8-9-18(20)22-23(28)21(13-16(3)4)30-25(32)19-7-6-11-29(19)26(33)27(30,34)24(22)31/h8-10,13-14,19,21,24,31,34H,6-7,11-12H2,1-5H3/t19-,21-,24-,27+/m0/s1

InChIKey

WEIYXEFMCIRZHC-MWGWWEMPSA-N

Smiles

c1(cc2c(cc1)c1c(n2C\C=C(/C)C)[C@H](\C=C(/C)C)N2C([C@H]3N(C([C@@]2(O)[C@H]1O)=O)CCC3)=O)OC

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 5400ug/kg (5.4mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Developments in Toxicology and Environtal Science. Vol. 12, Pg. 273, 1986.