Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Macromomycin protein
RN: 12634-34-3
InChIKey: HXKWEZFTHHFQMB-UHFFFAOYSA-N

Note

  • Weakly basic protein isolated from Streptomyces macromomyceticus; macromomycin is the apoprotein (MW=11kD) of auromomycin which is a chromophore called AUR-Chr (C35H33NO12) that is the cytotoxic component.

Molecular Formula

  • Unspecified

Molecular Weight

  • 249.2209
 

Classification Codes

  • Drug / Therapeutic Agent
  • Mutation Data
  • Natural Product
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Macromomycin protein

Synonyms

  • Macromomycin
  • Macromycin apoprotein, Streptomyces macromomyceticus
  • MCR
  • NSC 289642

Systematic Name

  • Macromomycin

Registry Numbers

CAS Registry Number

  • 12634-34-3

System Generated Number

  • 0012634343

Structure Descriptors

InChI

1S/C12H11NO5/c1-6-11(14)13-10-8(12(15)17-3)4-7(16-2)5-9(10)18-6/h4-5H,1H2,2-3H3,(H,13,14)

InChIKey

HXKWEZFTHHFQMB-UHFFFAOYSA-N

Smiles

COC(=O)c1cc(OC)cc2OC(=C)C(=O)Nc12

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD oral > 1500mg/kg (1500mg/kg)   Journal of Antibiotics. Vol. 29, Pg. 415, 1976.
mouse LD50 intraperitoneal 5100ug/kg (5.1mg/kg)   Journal of Antibiotics. Vol. 29, Pg. 415, 1976.
mouse LD50 intravenous 6400ug/kg (6.4mg/kg)   Journal of Antibiotics. Vol. 29, Pg. 415, 1976.