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Substance Name: Tetrachloroethylene [USP]
RN: 127-18-4
UNII: TJ904HH8SN
InChIKey: CYTYCFOTNPOANT-UHFFFAOYSA-N
Note
- A chlorinated hydrocarbon used as an industrial solvent and cooling liquid in electrical transformers. It is a potential carcinogen.
Molecular Formula
- C2-Cl4
Molecular Weight
- 165.834
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
Classification Codes
- Agricultural Chemical
- Carcinogens
- Drug / Therapeutic Agent
- Environmental Pollutants
- Fungicide, Bactericide, Wood Preservative
- Human Data
- Insecticide
- Mutation Data
- Nematocide
- Noxae
- Reproductive Effect
- Skin / Eye Irritant
- Solvents
- Tumor Data
Superlist Classification Codes
- 2007 CERCLA Priority List, Rank: 33
- 2011 CERCLA Priority List, Rank: 33
- Overall Carcinogenic Evaluation: Group 2A
- Reasonably Anticipated to be a Carcinogen
- Reportable Quantity (RQ) = 100 lb
- TWA (25 ppm); STEL (100 ppm); Confirmed animal carcinogen with unknown relevance to humans; BEI
- TWA 100 mg/m3; Ceiling 200 mg/m3, peak 300 in 5 min in any;
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Names and Synonyms
Name of Substance
- Tetrachloroethylene
- Tetrachloroethylene [USP]
MeSH Heading
- Tetrachloroethylene
Synonyms
- 1,1,2,2-Tetrachloroethene
- 1,1,2,2-Tetrachloroethylene
- 4-01-00-00715 (Beilstein Handbook Reference)
- AI3-01860
- Ankilostin
- Antisol 1
- BRN 1361721
- Carbon bichloride
- Carbon dichloride
- Caswell No. 827
- CCRIS 579
- Czterochloroetylen
- Czterochloroetylen [Polish]
- Didakene
- Dilatin PT
- Dow-per
- EC 204-825-9
- EINECS 204-825-9
- ENT 1,860
- EPA Pesticide Chemical Code 078501
- Ethene, tetrachloro-
- Ethylene tetrachloride
- Ethylene, tetrachloro-
- Fedal-UN
- HSDB 124
- NCI-C04580
- NSC 9777
- PCE
- Perawin
- Perc
- Perchloorethyleen, per
- Perchloorethyleen, per [Dutch]
- Perchlor
- Perchloraethylen, per
- Perchloraethylen, per [German]
- Perchlorethylene
- Perchlorethylene, per
- Perchlorethylene, per [French]
- Perchloroethylene
- Perclene
- Perclene D
- Percloroetilene
- Percloroetilene [Italian]
- Percosolv
- Percosolve
- PERK
- Perklone
- Persec
- RCRA waste number U210
- Tetlen
- Tetracap
- Tetrachlooretheen
- Tetrachlooretheen [Dutch]
- Tetrachloraethen
- Tetrachloraethen [German]
- Tetrachlorethylene
- Tetrachloroethene
- Tetrachloroethylene
- Tetrachloroethylene (IUPAC)
- Tetracloroetene
- Tetracloroetene [Italian]
- Tetraguer
- Tetraleno
- Tetralex
- Tetravec
- Tetroguer
- Tetropil
- UN 1897
- UNII-TJ904HH8SN
Systematic Names
- 1,1,2,2-Tetrachloroethylene
- Ethene, 1,1,2,2-tetrachloro-
- Ethene, tetrachloro-
- Ethylene, tetrachloro-
- Tetrachloroethylene
Superlist Names
- 1,1,2,2-Tetrachloroethylene
- Ethene, tetrachloro-
- Ethylene, tetrachloro-
- Perchloroethylene
- RCRA waste no. U210
- Tetrachloroethene
- Tetrachloroethylene
- Tetrachloroethylene [UN1897] [Poison]
- UN1897
Registry Numbers
CAS Registry Number
- 127-18-4
FDA UNII
- TJ904HH8SN
System Generated Number
- 0000127184
Structure Descriptors
InChI
InChI=1S/C2Cl4/c3-1(4)2(5)6InChIKey
CYTYCFOTNPOANT-UHFFFAOYSA-NSmiles
ClC(=C(Cl)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cat | LDLo | oral | 4gm/kg (4000mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: SLEEP | American Journal of Hygiene. Vol. 9, Pg. 430, 1929. |
child | TDLo | oral | 545mg/kg (545mg/kg) | BEHAVIORAL: COMA | Journal of Toxicology, Clinical Toxicology. Vol. 23, Pg. 103, 1985. |
dog | LD50 | intraperitoneal | 2100mg/kg (2100mg/kg) | LIVER: LIVER FUNCTION TESTS IMPAIRED | Toxicology and Applied Pharmacology. Vol. 10, Pg. 119, 1967. |
dog | LDLo | intravenous | 85mg/kg (85mg/kg) | Quarterly Journal of Pharmacy & Pharmacology. Vol. 7, Pg. 205, 1934. | |
dog | LDLo | oral | 4gm/kg (4000mg/kg) | BEHAVIORAL: SLEEP BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | American Journal of Hygiene. Vol. 9, Pg. 430, 1929. |
human | TCLo | inhalation | 96ppm/7H (96ppm) | BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" PERIPHERAL NERVE AND SENSATION: LOCAL ANESTHETIC SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE | National Technical Information Service. Vol. PB257-185, |
man | TCLo | inhalation | 600ppm/10M (600ppm) | SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE BEHAVIORAL: GENERAL ANESTHETIC | AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 5, Pg. 566, 1952. |
mouse | LC50 | inhalation | 5200ppm/4H (5200ppm) | Acta Pharmacologica et Toxicologica. Vol. 9, Pg. 303, 1953. | |
mouse | LD | intraperitoneal | > 500mg/kg (500mg/kg) | "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. Vol. 4, Pg. 378, 1952. | |
mouse | LD50 | oral | 8100mg/kg (8100mg/kg) | BEHAVIORAL: GENERAL ANESTHETIC | National Technical Information Service. Vol. PB257-185, |
mouse | LD50 | subcutaneous | 65gm/kg (65000mg/kg) | BEHAVIORAL: ATAXIA BEHAVIORAL: SLEEP | Journal of Pharmacology and Experimental Therapeutics. Vol. 123, Pg. 224, 1958. |
rabbit | LD | skin | > 3228mg/kg (3228mg/kg) | National Technical Information Service. Vol. AD-A180-198, | |
rabbit | LDLo | oral | 5gm/kg (5000mg/kg) | BEHAVIORAL: SLEEP BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | American Journal of Hygiene. Vol. 9, Pg. 430, 1929. |
rabbit | LDLo | subcutaneous | 2200mg/kg (2200mg/kg) | Quarterly Journal of Pharmacy & Pharmacology. Vol. 7, Pg. 205, 1934. | |
rat | LC50 | inhalation | 34200mg/m3/8H (34200mg/m3) | American Industrial Hygiene Association Journal. Vol. 20, Pg. 364, 1959. | |
rat | LD50 | intraperitoneal | 4678mg/kg (4678mg/kg) | Environmental Research. Vol. 40, Pg. 411, 1986. | |
rat | LD50 | oral | 2629mg/kg (2629mg/kg) | American Industrial Hygiene Association Journal. Vol. 20, Pg. 364, 1959. | |
rat | LDLo | intratracheal | 450mg/kg (450mg/kg) | National Technical Information Service. Vol. OTS0520615, |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | -2.23E+01 | deg C | EXP | |
Boiling Point | 121.3 | deg C | EXP | |
log P (octanol-water) | 3.4 | (none) | EXP | |
Water Solubility | 206 | mg/L | 25 | EXP |
Vapor Pressure | 18.5 | mm Hg | 25 | EXP |
Henry's Law Constant | 0.0177 | atm-m3/mole | 24 | EXP |
Atmospheric OH Rate Constant | 1.67E-13 | cm3/molecule-sec | 25 | EXP |
Physical property data is provided to ChemIDplus by SRC, Inc.