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Substance Name: Sulfapyridine sodium [NF]
RN: 127-57-1
UNII: H3SKB3662O
InChIKey: DAINBAXHBFSNCQ-UHFFFAOYSA-N

Note

  • Antibacterial, potentially toxic, used to treat certain skin diseases.

Classification Code

  • Drug / Therapeutic Agent

Molecular Formulas

  • C11-H10-N3-O2-S.Na
  • C11-H11-N3-O2-S.Na

Molecular Weight

  • 271.275
 
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Names and Synonyms

Name of Substance

  • Sulfapyridine sodium salt monohydrate
  • Sulfapyridine sodium [NF]

Synonyms

  • EINECS 204-850-5
  • N(sup 1)-2-Pyridylsulfanilamide sodium salt
  • Sodium sulfapymonohydrate
  • Sodium sulfapyridine
  • Sodium sulphapyridine
  • Soluble sulfapyridine
  • Soludagenan
  • Sulfanilamide, N(sup 1)-2-pyridyl-, monosodium salt
  • Sulfanilamide, N(sup 1)-2-pyridyl-, N(sup 1)-sodium deriv.
  • Sulfapyridine sodium
  • Sulfapyridine, sodium salt
  • UNII-H3SKB3662O

Systematic Names

  • Benzenesulfonamide, 4-amino-N-2-pyridinyl-, monosodium salt
  • Benzenesulfonamide, 4-amino-N-2-pyridinyl-, sodium salt (1:1)
  • Sodium, (N(sup 1)-2-pyridylsulfanilamido)-
  • Sulfapyridine sodium

Registry Numbers

CAS Registry Number

  • 127-57-1

FDA UNII

  • H3SKB3662O

Other Registry Number

  • 1334-68-5

System Generated Number

  • 0000127571

Molecular Formulas

Molecular Formulas

  • C11-H10-N3-O2-S.Na
  • C11-H11-N3-O2-S.Na

Molecular Formula Fragments

  • C11-H10-N3-O2-S
  • C11-H11-N3-O2-S
  • COMPONENT
  • Na

Structure Descriptors

InChI

1S/C11H10N3O2S.Na/c12-9-4-6-10(7-5-9)17(15,16)14-11-3-1-2-8-13-11;/h1-8H,12H2;/q-1;+1

InChIKey

DAINBAXHBFSNCQ-UHFFFAOYSA-N

Smiles

c1ccnc(c1)[N-]S(=O)(=O)c2ccc(cc2)N.[Na+]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 intravenous 693mg/kg (693mg/kg)   Journal of the Indiana State Medical Association. Vol. 33, Pg. 503, 1940.
monkey LDLo intravenous 600mg/kg (600mg/kg)   Journal of the Indiana State Medical Association. Vol. 33, Pg. 503, 1940.
mouse LD50 intramuscular 1096mg/kg (1096mg/kg)   Journal of the Indiana State Medical Association. Vol. 33, Pg. 503, 1940.
mouse LD50 intraperitoneal 910mg/kg (910mg/kg)   Journal of the Indiana State Medical Association. Vol. 33, Pg. 503, 1940.
mouse LD50 intravenous 696mg/kg (696mg/kg)   Journal of the Indiana State Medical Association. Vol. 33, Pg. 503, 1940.
mouse LD50 oral 2gm/kg (2000mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 68, Pg. 259, 1940.
mouse LD50 parenteral 1gm/kg (1000mg/kg)   Proceedings of the Society for Experimental Biology and Medicine. Vol. 43, Pg. 328, 1940.
mouse LD50 subcutaneous 872mg/kg (872mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 71, Pg. 138, 1941.
rat LD50 intravenous 648mg/kg (648mg/kg)   Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 33, Pg. 80, 1944.
rat LD50 oral 2994mg/kg (2994mg/kg)   Journal of the Indiana State Medical Association. Vol. 33, Pg. 503, 1940.
rat LDLo intraperitoneal 1120mg/kg (1120mg/kg)   Proceedings of the Society for Experimental Biology and Medicine. Vol. 45, Pg. 15, 1940.