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Substance Name: Sulfamerazine sodium [Injection] [INN:NF]
RN: 127-58-2
UNII: JOV4UJY07O
InChIKey: BSFJGCCAXDCMOX-UHFFFAOYSA-N

Note

  • A sulfanilamide that is used as an antibacterial agent.

Classification Code

  • Drug / Therapeutic Agent

Molecular Formulas

  • C11-H11-N4-Na-O2-S
  • C11-H11-N4-O2-S.Na
  • C11-H12-N4-O2-S.Na

Molecular Weight

  • 286.2899
 
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Names and Synonyms

Name of Substance

  • Sulfamerazine sodium [Injection] [INN:NF]
  • Sulfamerazine sodium [INN]

Synonyms

  • 2-Sulfanilamido-4-methylpyrimidine sodium salt
  • 4-Methyl-2-sulfanilamidopyrimidine sodium salt
  • EINECS 204-851-0
  • Monosodium 2-sulfanilamido-4-methylpyrimidine
  • N(sup 1)-(4-Methyl-2-pyrimidinyl)sulfanilamide sodium salt
  • NSC 226823
  • Sodium derivate of N1-(4-methyl-2-pyrimidinyl)sulfanilamide
  • Sodium sulfamerazine
  • Sodium sulphamerazine
  • Solfamerazina sodica
  • Solfamerazina sodica [DCIT]
  • Soluble sulfamerazine
  • Solumedine
  • Sulfamerazin natrium
  • Sulfamerazina sodica
  • Sulfamerazina sodica [INN-Spanish]
  • Sulfamerazine sodique
  • Sulfamerazine sodique [INN-French]
  • Sulfamerazine sodium
  • Sulfamerazine sodium Injection
  • Sulfamerazine sodium [Injection]
  • Sulfamerazinum natricum
  • Sulfamerazinum natricum [INN-Latin]
  • UNII-JOV4UJY07O

Systematic Names

  • Benzenesulfonamide, 4-amino-N-(4-methyl-2-pyrimidinyl)-, monosodium salt
  • Benzenesulfonamide, 4-amino-N-(4-methyl-2-pyrimidinyl)-, monosodium salt (9CI)
  • Benzenesulfonamide, 4-amino-N-(4-methyl-2-pyrimidinyl)-, sodium salt (1:1)
  • Sulfamerazine sodium
  • Sulfanilamide, N(sup 1)-(4-methyl-2-pyrimidinyl)-, monosodium salt
  • Sulfanilamide, N1-(4-methyl-2-pyrimidinyl)-, monosodium salt (8CI)

Registry Numbers

CAS Registry Number

  • 127-58-2

FDA UNII

  • JOV4UJY07O

System Generated Number

  • 0000127582

Molecular Formulas

Molecular Formulas

  • C11-H11-N4-Na-O2-S
  • C11-H11-N4-O2-S.Na
  • C11-H12-N4-O2-S.Na

Molecular Formula Fragments

  • C11-H11-N4-O2-S
  • C11-H12-N4-O2-S
  • COMPONENT
  • Na

Structure Descriptors

InChI

1S/C11H11N4O2S.Na/c1-8-6-7-13-11(14-8)15-18(16,17)10-4-2-9(12)3-5-10;/h2-7H,12H2,1H3;/q-1;+1

InChIKey

BSFJGCCAXDCMOX-UHFFFAOYSA-N

Smiles

Cc1ccnc(n1)[N-]S(=O)(=O)c2ccc(cc2)N.[Na+]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 1522mg/kg (1522mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 81, Pg. 17, 1944.
mouse LD50 intravenous 900mg/kg (900mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 94, Pg. 338, 1953.
mouse LD50 oral 2800mg/kg (2800mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 94, Pg. 338, 1953.
mouse LD50 subcutaneous 1739mg/kg (1739mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 81, Pg. 17, 1944.