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Substance Name: Connexin 26
RN: 127120-53-0


  • A gap junction protein encoded by the Gap Junction Beta 2 or GJB2 gene. In the cochlea and epidermis, its hexamers form channels between cells that open to allow cell-to-cell diffusion of small molecules as well as recycling of potassium. Mutations in Connexin 26 are associated with congenital SENSORINEURAL HEARING LOSS.
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Names and Synonyms

Name of Substance

  • Connexin 26

MeSH Heading

  • Connexin 26


  • beta2 Connexin
  • Connexin Cx26
  • Cx26 Gene product

Systematic Name

  • Connexin 26 (rat clone Cx26-1/Cx26-2 reduced)

Registry Numbers

CAS Registry Number

  • 127120-53-0

System Generated Number

  • 0127120530