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Substance Name: Vascular endothelial growth factor
RN: 127464-60-2


  • The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as "tumor angiogenesis factor" and "vascular permeability factor". Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced.
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Names and Synonyms

Name of Substance

  • Vascular endothelial growth factor
  • Vasculotropin

MeSH Heading

  • Vascular Endothelial Growth Factor A


  • Vascular endothelial growth factor
  • Vascular endotheolial growth factor

Systematic Name

  • Vasculotropin

Registry Numbers

CAS Registry Number

  • 127464-60-2

System Generated Number

  • 0127464602