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Substance Name: A 204
RN: 12750-79-7
InChIKey: RHDSQRNKIIRGBB-UHFFFAOYSA-N

Note

  • Polyether monocarboxylic acid antibiotic; crystalline isolate from fermentation of strain of Streptomyces albus.

Classification Code

  • Drug / Therapeutic Agent

Molecular Weight

  • 945.1856
 
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Names and Synonyms

Name of Substance

  • A 204

Synonym

  • A204

Systematic Name

  • Antibiotic A204

Registry Numbers

CAS Registry Number

  • 12750-79-7

Related Registry Number

  • 43110-10-7 (hydrochloride salt)

System Generated Number

  • 0012750797

Structure Descriptors

InChI

1S/C49H84O17/c1-24-40(56-13)26(3)47(10,52)65-41(24)35-17-16-33(60-35)34-18-20-37(61-34)46(9)42(57-14)28(5)49(66-46)25(2)36(55-12)22-31(63-49)23-38-45(8,58-15)43(27(4)48(53,64-38)29(6)44(50)51)62-39-21-19-32(54-11)30(7)59-39/h24-43,52-53H,16-23H2,1-15H3,(H,50,51)

InChIKey

RHDSQRNKIIRGBB-UHFFFAOYSA-N

Smiles

COC1CCC(OC2C(C)C(O)(OC(CC3CC(OC)C(C)C4(O3)OC(C)(C5CCC(O5)C6CCC(O6)C7OC(C)(O)C(C)C(OC)C7C)C(OC)C4C)C2(C)OC)C(C)C(=O)O)OC1C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
chicken LD50 oral 51mg/kg (51mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: FOOD INTAKE (ANIMAL)

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Antimicrobial Agents and Chemotherapy Vol. -, Pg. 357, 1970.
mouse LD50 oral 8mg/kg (8mg/kg) BEHAVIORAL: FOOD INTAKE (ANIMAL)

BEHAVIORAL: MUSCLE WEAKNESS

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Antimicrobial Agents and Chemotherapy Vol. -, Pg. 357, 1970.
rat LD50 oral 7mg/kg (7mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: FOOD INTAKE (ANIMAL)

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Antimicrobial Agents and Chemotherapy Vol. -, Pg. 357, 1970.