Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Tolytoxin
RN: 127999-44-4
InChIKey: FTGOWEQDZZMPNJ-RWAMPESTSA-N

Note

  • From three species of Scytonema.

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C46-H75-N-O13

Molecular Weight

  • 850.093
 
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Tolytoxin

Synonyms

  • 6-Hydroxy-7-O-methylscytophycin B
  • Tolytoxin

Systematic Names

  • Scytophycin B, 6-hydroxy-7-O-methyl-
  • Swinholide A, 27,31-deepoxy-31,32-didehydro-16,34-epoxy-32-(formylmethylamino)-6-hydroxy-28,30-dimethyl-7,17,19-tri-O-methyl-27-oxo-

Registry Numbers

CAS Registry Number

  • 127999-44-4

System Generated Number

  • 0127999444

Structure Descriptors

InChI

1S/C46H75NO13/c1-28-16-19-42(51)60-45(33(6)43(52)29(2)17-18-36(49)31(4)44(57-12)30(3)20-21-47(7)27-48)32(5)38(53-8)25-41(56-11)46(26-58-46)40(55-10)24-35-15-13-14-34(59-35)23-39(54-9)37(50)22-28/h13-14,16,19-22,27,29-35,37-41,43-45,50,52H,15,17-18,23-26H2,1-12H3/b19-16+,21-20+,28-22-/t29-,30+,31-,32-,33-,34-,35-,37-,38+,39+,40-,41-,43-,44+,45-,46-/m0/s1

InChIKey

FTGOWEQDZZMPNJ-RWAMPESTSA-N

Smiles

C1=C[C@@H]2O[C@@H](C1)C[C@@H]([C@@]1(CO1)[C@H](C[C@H]([C@H](C)[C@@H]([C@H]([C@H]([C@H](CCC([C@@H]([C@@H]([C@@H](\C=C\N(C)C=O)C)OC)C)=O)C)O)C)OC(C=CC(=C[C@H](O)[C@@H](OC)C2)C)=O)OC)OC)OC

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 1500ug/kg (1.5mg/kg) BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: CYANOSIS

BEHAVIORAL: COMA
Archives of Microbiology. Vol. 157, Pg. 406, 1992.