Skip Navigation
ChemIDplus A TOXNET DATABASE Lite•Browse•Advanced

Substance Name: Ergonovine maleate [USP]
RN: 129-51-1
UNII: YMH3D0ZJWV
InChIKey: YREISLCRUMOYAY-IIPCNOPRSA-N

Note

  • An ergot alkaloid (ERGOT ALKALOIDS) with uterine and vascular smooth muscle contractile properties.

Molecular Formula

  • C19-H23-N3-O2.C4-H4-O4

Molecular Weight

  • 441.481
 

Classification Codes

  • Human Data
  • Mutation Data
  • Natural Product
  • Oxytocic
  • Reproductive Effect
  • Tumor Data
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Regulatory Agencies (Superlist Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Ergonovine maleate
  • Ergonovine maleate [USP]

Synonyms

  • 9,10-Didehydro-N-((S)-2-hydroxy-1-methylethyl)-6-methylergoline-8beta-carboxamide maleate (1:1) (salt)
  • Cornocentin
  • Crude ergot
  • D-Ergonovine maleate
  • EINECS 204-953-5
  • Ergoline-8-carboxamide, 9,10-didehydro-N-(2-hydroxy-1-methylethyl)-6-methyl-, (8beta(S))-, (Z)-2-butenedioate (1:1) (salt)
  • Ergomet
  • Ergometrin maleate
  • Ergometrine acid maleate
  • Ergometrine hydrogen maleate
  • Ergometrine maleate
  • Ergometrine maleate (1:1)
  • Ergonovine hydrogen maleate
  • Ergonovine maleate
  • Ergonovine, maleate (1:1)
  • Ergonovine, maleate (1:1) (salt)
  • Ergotocin maleate
  • Ergotrate
  • Ergotrate Maleate
  • Ermetrin
  • Metriclavin
  • NSC 93752
  • Oxytocic
  • UNII-YMH3D0ZJWV

Systematic Names

  • Ergoline-8-beta-carboxamide, 9,10-didehydro-N-((S)-2-hydroxy-1-methylethyl)-6-methyl-, maleate (1:1) (salt)
  • Ergoline-8-carboxamide, 9,10-didehydro-N-((1S)-2-hydroxy-1-methylethyl)-6-methyl-, (8beta)-, (2Z)-2-butenedioate (1:1) (salt)
  • Ergoline-8-carboxamide, 9,10-didehydro-N-(2-hydroxy-1-methylethyl)-6-methyl-, (8beta(S))-, (Z)-2-butenedioate (1:1) (salt)
  • Ergometrine hydrogen maleate

Registry Numbers

CAS Registry Number

  • 129-51-1

FDA UNII

  • YMH3D0ZJWV

Other Registry Numbers

  • 6815-20-9
  • 78207-84-8
  • 912-07-2

System Generated Number

  • 0000129511

Molecular Formulas

Molecular Formula

  • C19-H23-N3-O2.C4-H4-O4

Molecular Formula Fragments

  • C19-H23-N3-O2
  • C4-H4-O4
  • COMPONENT

Structure Descriptors

InChI

1S/C19H23N3O2.C4H4O4/c1-11(10-23)21-19(24)13-6-15-14-4-3-5-16-18(14)12(8-20-16)7-17(15)22(2)9-13;5-3(6)1-2-4(7)8/h3-6,8,11,13,17,20,23H,7,9-10H2,1-2H3,(H,21,24);1-2H,(H,5,6)(H,7,8)/b;2-1-/t11-,13+,17+;/m0./s1

InChIKey

YREISLCRUMOYAY-IIPCNOPRSA-N

Smiles

C(\C=C/C(O)=O)(=O)O.c12[nH]cc3c2c(ccc1)C=1[C@@H]([N@@](C[C@@H](C1)C(N[C@H](CO)C)=O)C)C3

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LDLo intravenous 80mg/kg (80mg/kg) SKIN AND APPENDAGES (SKIN): HAIR: OTHER

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD		 Journal of Pharmacology and Experimental Therapeutics. Vol. 54, Pg. 398, 1935.
infant TDLo intramuscular 40ug/kg (0.04mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

LUNGS, THORAX, OR RESPIRATION: CYANOSIS		 JAMA, Journal of the American Medical Association. Vol. 250, Pg. 729, 1983.
man LDLo unreported 15mg/kg (15mg/kg)   "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.
mouse LD50 intravenous 8260ug/kg (8.26mg/kg)   Toxicology and Applied Pharmacology. Vol. 23, Pg. 537, 1972.