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Substance Name: Ergonovine maleate [USP]
RN: 129-51-1
UNII: YMH3D0ZJWV
InChIKey: YREISLCRUMOYAY-IIPCNOPRSA-N
Note
- An ergot alkaloid (ERGOT ALKALOIDS) with uterine and vascular smooth muscle contractile properties.
Molecular Formula
- C19-H23-N3-O2.C4-H4-O4
Molecular Weight
- 441.481
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- Human Data
- Mutation Data
- Natural Product
- Oxytocic
- Reproductive Effect
- Tumor Data
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Names and Synonyms
Name of Substance
- Ergonovine maleate
- Ergonovine maleate [USP]
Synonyms
- 9,10-Didehydro-N-((S)-2-hydroxy-1-methylethyl)-6-methylergoline-8beta-carboxamide maleate (1:1) (salt)
- Cornocentin
- Crude ergot
- D-Ergonovine maleate
- EINECS 204-953-5
- Ergoline-8-carboxamide, 9,10-didehydro-N-(2-hydroxy-1-methylethyl)-6-methyl-, (8beta(S))-, (Z)-2-butenedioate (1:1) (salt)
- Ergomet
- Ergometrin maleate
- Ergometrine acid maleate
- Ergometrine hydrogen maleate
- Ergometrine maleate
- Ergometrine maleate (1:1)
- Ergonovine hydrogen maleate
- Ergonovine maleate
- Ergonovine, maleate (1:1)
- Ergonovine, maleate (1:1) (salt)
- Ergotocin maleate
- Ergotrate
- Ergotrate Maleate
- Ermetrin
- Metriclavin
- NSC 93752
- UNII-YMH3D0ZJWV
Systematic Names
- Ergoline-8-beta-carboxamide, 9,10-didehydro-N-((S)-2-hydroxy-1-methylethyl)-6-methyl-, maleate (1:1) (salt)
- Ergoline-8-carboxamide, 9,10-didehydro-N-((1S)-2-hydroxy-1-methylethyl)-6-methyl-, (8beta)-, (2Z)-2-butenedioate (1:1) (salt)
- Ergoline-8-carboxamide, 9,10-didehydro-N-(2-hydroxy-1-methylethyl)-6-methyl-, (8beta(S))-, (Z)-2-butenedioate (1:1) (salt)
- Ergometrine hydrogen maleate
Registry Numbers
CAS Registry Number
- 129-51-1
FDA UNII
- YMH3D0ZJWV
Other Registry Numbers
- 6815-20-9
- 78207-84-8
- 912-07-2
System Generated Number
- 0000129511
Molecular Formulas
Molecular Formula
- C19-H23-N3-O2.C4-H4-O4
Molecular Formula Fragments
- C19-H23-N3-O2
- C4-H4-O4
- COMPONENT
Structure Descriptors
InChI
InChI=1S/C19H23N3O2.C4H4O4/c1-11(10-23)21-19(24)13-6-15-14-4-3-5-16-18(14)12(8-20-16)7-17(15)22(2)9-13;5-3(6)1-2-4(7)8/h3-6,8,11,13,17,20,23H,7,9-10H2,1-2H3,(H,21,24);1-2H,(H,5,6)(H,7,8)/b;2-1-/t11-,13+,17+;/m0./s1InChIKey
YREISLCRUMOYAY-IIPCNOPRSA-NSmiles
C[C@@H](CO)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LDLo | intravenous | 80mg/kg (80mg/kg) | SKIN AND APPENDAGES (SKIN): HAIR: OTHER BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of Pharmacology and Experimental Therapeutics. Vol. 54, Pg. 398, 1935. |
infant | TDLo | intramuscular | 40ug/kg (0.04mg/kg) | GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" LUNGS, THORAX, OR RESPIRATION: CYANOSIS | JAMA, Journal of the American Medical Association. Vol. 250, Pg. 729, 1983. |
man | LDLo | unreported | 15mg/kg (15mg/kg) | "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970. | |
mouse | LD50 | intravenous | 8260ug/kg (8.26mg/kg) | Toxicology and Applied Pharmacology. Vol. 23, Pg. 537, 1972. |