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Substance Name: Sulfamidopyrine sodium
RN: 129-89-5
UNII: 5VPH1208TA
InChIKey: ZFDPAZDODACYOG-UHFFFAOYSA-M

Classification Codes

  • Analgesic
  • Antipyretic
  • Drug / Therapeutic Agent

Molecular Formula

  • C12-H15-N3-O4-S.Na

Molecular Weight

  • 319.3156
 
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Names and Synonyms

Name of Substance

  • Sulfamidopyrine sodium

Synonyms

  • 1-Phenyl-2,3-dimethyl-4-amino-5-pyrazolon-N-methanesulfonsaeuren natrium
  • 1-Phenyl-2,3-dimethyl-4-amino-5-pyrazolon-N-methanesulfonsaeuren natrium [German]
  • Amizole
  • Amizole (pharmaceutical)
  • Melaminsulfon
  • Melaminsulfone
  • Melubrin
  • N-(2,3-Dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)aminomethansulfonsaeure natriumsalz
  • Pyrazogin
  • Sulfamidopyrin-Natrium
  • Sulfamidopyrine [WHO-DD]
  • Sulfamipyrine
  • Sulphamipyrin
  • UNII-5VPH1208TA

Systematic Name

  • Methanesulfonic acid, (antipyrinylamino)-, monosodium salt

Registry Numbers

CAS Registry Number

  • 129-89-5

FDA UNII

  • 5VPH1208TA

System Generated Number

  • 0000129895

Molecular Formulas

Molecular Formula

  • C12-H15-N3-O4-S.Na

Molecular Formula Fragments

  • C12-H15-N3-O4-S
  • COMPONENT
  • Na

Structure Descriptors

InChI

1S/C12H15N3O4S.Na/c1-9-11(13-8-20(17,18)19)12(16)15(14(9)2)10-6-4-3-5-7-10;/h3-7,13H,8H2,1-2H3,(H,17,18,19);/q;+1/p-1

InChIKey

ZFDPAZDODACYOG-UHFFFAOYSA-M

Smiles

[Na+].CN1N(C(=O)C(=C1C)NCS(=O)(=O)[O-])c2ccccc2

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LDLo subcutaneous 4500mg/kg (4500mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 5, Pg. 213, 1955.
mouse LDLo subcutaneous 5gm/kg (5000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: EXCITEMENT
"Pharmakologische Prufung von Analgetika, Dissertation," Herrlen, G., Pharmakologischen Institut der Universitat Tubingen, Fed. Rep. Ger., 1933Vol. -, Pg. -, 1933.
rabbit LDLo subcutaneous 3500mg/kg (3500mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 5, Pg. 213, 1955.
rat LDLo subcutaneous 4500mg/kg (4500mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 5, Pg. 213, 1955.