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Substance Name: Aripiprazole [USAN:INN:BAN]
RN: 129722-12-9
UNII: 82VFR53I78
InChIKey: CEUORZQYGODEFX-UHFFFAOYSA-N
Notes
- A piperazine and quinolone derivative that is used primarily as an antipsychotic agent. It is a partial agonist of SEROTONIN RECEPTOR, 5-HT1A and DOPAMINE D2 RECEPTORS, where it also functions as a post-synaptic antagonist, and an antagonist of SEROTONIN RECEPTOR, 5-HT2A. It is used for the treatment of SCHIZOPHRENIA and BIPOLAR DISORDER, and as an adjunct therapy for the treatment of depression.
- Has both presynaptic dopamine autoreceptor agonistic activity and postsynaptic D2 receptor antagonistic activity; use associated with HYPERGLYCEMIA.
Molecular Formula
- C23-H27-Cl2-N3-O2
Molecular Weight
- 448.391
Classification Codes
- Antidepressive Agents
- Antipsychotic
- Antipsychotic Agents
- Antischizophrenic
- Central Nervous System Agents
- Central Nervous System Depressants
- Dopamine Agents
- Dopamine Agonists
- Dopamine Antagonists
- Dopamine D2 Receptor Antagonists
- Neurotransmitter Agents
- Psychotropic Drugs
- Serotonin 5-HT1 Receptor Agonists
- Serotonin 5-HT2 Receptor Antagonists
- Serotonin Agents
- Serotonin Antagonists
- Serotonin Receptor Agonists
- Tranquilizing Agents
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Names and Synonyms
Name of Substance
- Aripiprazole
- Aripiprazole [USAN:INN:BAN]
MeSH Heading
- Aripiprazole
Synonyms
- 7-(4-(4-(2,3-Dichlorophenyl)-1-piperazinyl)butoxy)-3,4-dihydro-2(1H)-quinolinone
- 7-(4-(4-(2,3-Dichlorophenyl)-1-piperazinyl)butoxy)-3,4-dihydrocarbostyril
- 7-(4-(4-(2,3-Dichlorophenyl)-1-piperazinyl)butyloxy)-3,4-dihydro-2(1H)-quinolinone
- Abilify
- Abilify Digital
- Abilify Discmelt
- Abilify Maintena
- Abilify Maintena Kit
- Abilify MyCite
- Abilitat
- Aripiprazole
- Discmelt
- HSDB 7320
- NSC 759266
- Opc 14597
- OPC 31
- OPC-14597
- OPC-31
- UNII-82VFR53I78
Systematic Name
- 2(1H)-Quinolinone, 7-(4-(4-(2,3-dichlorophenyl)-1-piperazinyl)butoxy)-3,4-dihydro-
Registry Numbers
CAS Registry Number
- 129722-12-9
FDA UNII
- 82VFR53I78
System Generated Number
- 0129722129