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Substance Name: Eptotermin alfa [INN:BAN]
RN: 129805-33-0
UNII: IT063R5MY0

Note

  • A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a potent osteogenic factor and a specific regulator of nephrogenesis.

Molecular Formula

  • (C683-H1061-N197-O208-S10)2

Molecular Weight

  • 15674.6785
 

Classification Code

  • Growth Factor
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Links to Resources

Names and Synonyms

Name of Substance

  • Bone morphogenetic protein 7
  • Eptotermin alfa [INN:BAN]

MeSH Heading

  • Bone morphogenetic protein 7

Synonyms

  • Bone morphogenetic protein 7
  • Eptotermin alfa
  • HrBMP-7
  • Human recombinant bone morphogenetic protein 7 (hrBMP-7) or osteogenic protein-1 (OP-1)
  • OP-1
  • Opgenra
  • Osigraft
  • UNII-IT063R5MY0

Systematic Names

  • Human recombinant bone morphogenetic protein 7
  • Osteogenic Protein-1

Registry Numbers

CAS Registry Number

  • 129805-33-0

FDA UNII

  • IT063R5MY0

Other Registry Numbers

  • 133606-73-2
  • 134548-31-5
  • 199945-19-2

System Generated Number

  • 0129805330

Molecular Formulas

Molecular Formula

  • (C683-H1061-N197-O208-S10)2

Molecular Formula Fragment

  • C683-H1061-N197-O208-S10

Structure Descriptors

Smiles

CC[C@H](C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]4CCCN4C(=O)[C@H](Cc5ccccc5)NC(=O)[C@H](C)NC(=O)[C@@H]6CSSC[C@H](NC(=O)CNC(=O)[C@@H]7CSSC[C@H](NC(=O)[C@H](Cc8ccc(O)cc8)NC(=O)[C@H](Cc9ccc(O)cc9)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](Cc%10ccc(O)cc%10)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]%11CCCN%11C(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc%12c[nH]c%13ccccc%12%13)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](Cc%14c[nH]c%15ccccc%14%15)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc%16ccccc%16)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc%17ccc(O)cc%17)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc%18cnc[nH]%18)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CS)NC(=O)[C@@H]%19CCCN%19C(=O)[C@H](CCCCN)NC(=O)[C@@H]%20CCCN%20C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]%21CCCN%21C(=O)[C@H](CC(=O)N)NC(=O)[C@@H](NC(=O)[C@H](Cc%22ccccc%22)NC(=O)[C@H](Cc%23cnc[nH]%23)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)N)NC(=O)[C@@H](NC1=O)C(C)C)[C@@H](C)O)C(C)C)[C@@H](C)CC)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N%24CCC[C@H]%24C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc%25ccc(O)cc%25)C(=O)N[C@@H](Cc%26ccccc%26)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc%27ccc(O)cc%27)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N7)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](C)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]%28CCCN%28C(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](N)CO)[C@@H](C)O)[C@@H](C)O)C(C)C)C(C)C)[C@@H](C)CC)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N6)C(=O)N[C@@H](Cc%29cnc[nH]%29)C(=O)O)[C@@H](C)O