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Substance Name: Ethionine
RN: 13073-35-3
UNII: WX1BN24WZT
InChIKey: GGLZPLKKBSSKCX-YFKPBYRVSA-N

Note

  • 2-Amino-4-(ethylthio)butyric acid. An antimetabolite and methionine antagonist that interferes with amino acid incorporation into proteins and with cellular ATP utilization. It also produces liver neoplasms.

Molecular Formula

  • C6-H13-N-O2-S

Molecular Weight

  • 163.2397
 

Classification Codes

  • Antimetabolites
  • Mutation Data
  • Noxae
  • Tumor Data
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Names and Synonyms

Results Name

  • Ethionine

Name of Substance

  • (L)-Ethionine
  • Ethionine

MeSH Heading

  • Ethionine

Synonyms

  • 4-04-00-03194 (Beilstein Handbook Reference)
  • BRN 1722528
  • Butanoic acid, 2-amino-4-(ethylthio)-, (S)-
  • Butyric acid, 2-amino-4-(ethylene)-, L-
  • CCRIS 289
  • EINECS 235-966-4
  • ETH
  • Ethionine
  • Ethionine (VAN)
  • Homocysteine, S-ethyl-
  • HSDB 5080
  • L-2-Amino-4-(ethylthio)butyric acid
  • L-Ethionine
  • L-Homocysteine, S-ethyl-
  • L-S-Ethylhomocysteine
  • NSC 82393
  • UNII-WX1BN24WZT

Systematic Names

  • Butyric acid, 2-amino-4-(ethylthio)-, L-
  • L-Ethionine
  • L-Homocysteine, S-ethyl-
  • S-Ethyl-L-homocysteine

Registry Numbers

CAS Registry Number

  • 13073-35-3

FDA UNII

  • WX1BN24WZT

Other Registry Numbers

  • 55-17-4
  • 89955-21-5

System Generated Number

  • 0013073353

Structure Descriptors

InChI

1S/C6H13NO2S/c1-2-10-4-3-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1

InChIKey

GGLZPLKKBSSKCX-YFKPBYRVSA-N

Smiles

[C@@H](CCSCC)(N)C(=O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LD intraperitoneal > 1gm/kg (1000mg/kg) LIVER: OTHER CHANGES

LIVER: CHANGES IN LIVER WEIGHT
Acta Pathologica Japonica. Vol. 39, Pg. 281, 1989.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 195 deg C   EXP
log P (octanol-water) -1.920 (none)   EST
Atmospheric OH Rate Constant 5.77E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.