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Substance Name: Silteplase [INN:JAN]
RN: 131081-40-8

Classification Codes

  • Drug / Therapeutic Agent
  • Natural Product

Molecular Formula

  • C2580-H3948-N752-O784-S40
 
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Names and Synonyms

Name of Substance

  • Silteplase
  • Silteplase [INN:JAN]

Synonyms

  • N-(N(sup 2)-(N-glycyl-L-alanyl)-L-arginyl)plasminogen activator (human tissue-type protein moiety reduced), glycoform
  • Silteplasa
  • Silteplasa [INN-Spanish]
  • Silteplase
  • Silteplasum
  • Silteplasum [INN-Latin]

Systematic Names

  • N-(N(sup 2)-(N-glycyl-L-alanyl)-L-arginyl)plasminogen activator (human tissue-type protein moiety reduced), glycoform
  • Plasminogen activator (human Tissue-type protein moiety reduced), N-(N2-(N-glycyl-L-alanyl)-L-arginyl)-, glycoform

Registry Numbers

CAS Registry Number

  • 131081-40-8

System Generated Number

  • 0131081408

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
monkey LD50 intravenous > 30mg/kg (30mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 769, 1991.
mouse LD50 intravenous > 30mg/kg (30mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 769, 1991.
mouse LD50 oral > 30mg/kg (30mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 769, 1991.
rat LD50 intravenous > 30mg/kg (30mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 769, 1991.
rat LD50 oral > 30mg/kg (30mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 769, 1991.