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Substance Name: Vofatamab [USAN]
RN: 1312305-12-6
UNII: JMH6YR91PG

Note

  • An IgG1antibody to FGFR3 for the treatment of t(4;14)-positive multiple myeloma.

Molecular Formula

  • C6496-H10040-N1716-O2050-S44 (non-glycosylated)
 

Classification Code

  • Treatment of Relapsed or Refractory Advanced Urothelial Cell Carcinoma (UCC)
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Names and Synonyms

Name of Substance

  • Vofatamab [USAN]

Synonyms

  • Anti-FGR3
  • B-701
  • Immunoglobulin G1-kappa, anti-(Homo sapiens Fibroblast growth factor receptor 3 (FGFR-3, antigen CD333)); humanized monoclonal antibody; gamma1 heavy chain (1-457) (Homo sapiens VH (IGHV3-66*01 (86%) -(IGHD)-IGHJ4*01) (8.8.20) (1-127) -Homo sapiens IGHG1*03 (CH1(R97>K(224))) (128-457)) (230-214')-disulfide with kappa light chain (1'-214') (Homo sapiens V-KAPPA (IGKV1-5*01 (87%) -IGKJ1*01)(6.3.9) (1'-107') -Homo sapiens IGKC*01 (108'-214')), dimer (236-236'':239-239'')-bisdisulfide
  • MFGR-1877A
  • MFGR-1877S
  • MFGR1877A
  • MFGR1877S
  • RG-7444
  • UNII-JMH6YR91PG
  • Vofatamab

Systematic Name

  • Immunoglobulin G1, anti-(human fibroblast growth factor receptor type 3) (human monoclonal MFGR1877S heavy chain), disulfide with human monoclonal MFGR1877S kappa-chain, dimer

Registry Numbers

CAS Registry Number

  • 1312305-12-6

FDA UNII

  • JMH6YR91PG

System Generated Number

  • 1312305126