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Substance Name: Polatuzumab vedotin [USAN:INN]
RN: 1313206-42-6
UNII: KG6VO684Z6

Note

  • Consists of an anti-CD79B monoclonal antibody conjugated to monomethyl auristatin E.

Molecular Formula

  • C68-H106-N11-O15-S

Molecular Weight

  • 1349.7134
 
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Names and Synonyms

Name of Substance

  • Polatuzumab vedotin
  • Polatuzumab vedotin [USAN:INN]

Synonyms

  • ACD-79B-VCMMAE
  • ACD-79BVCMMAE
  • ACD79B-VCMMAE
  • DCDS-4501A
  • DCDS4501A
  • FCU 2711
  • FCU-2711
  • FCU2711
  • Polatuzumab vedotin
  • Polatuzumab vedotin-PIIQ
  • Polivy
  • RG-7596
  • RG7596
  • Ro 5541077-000
  • RO-5541077-000
  • RO-5541077000
  • RO5541077-000
  • UNII-KG6VO684Z6

Registry Numbers

CAS Registry Number

  • 1313206-42-6

FDA UNII

  • KG6VO684Z6

System Generated Number

  • 1313206426

Structure Descriptors

Smiles

[*]SC1CC(=O)N(CCCCCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(=O)N)C(=O)Nc2ccc(COC(=O)N(C)[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N(C)[C@@H]([C@@H](C)CC)[C@@H](CC(=O)N3CCC[C@H]3[C@H](OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)c4ccccc4)OC)cc2)C1=O