Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: KRN 8602
RN: 131722-57-1
InChIKey: ZDJRSUWWMAYYID-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C30-H35-N-O11.Cl-H

Molecular Weight

  • 622.063
 
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Results Name

  • KRN 8602

Synonyms

  • 3'-Deamino-3'-morpholino-13-deoxo-10-hydroxycarminomycin hydrochloride
  • KRN 8602
  • MX2 hydrochloride

Systematic Name

  • 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-8-ethyl-10-((3-(4-morpholinyl)-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-1,6,7,8,11-pentahydroxy-, hydrochloride, (7R-(7-alpha,8-beta,10-beta))-

Registry Numbers

CAS Registry Number

  • 131722-57-1

System Generated Number

  • 0131722571

Molecular Formulas

Molecular Formula

  • C30-H35-N-O11.Cl-H

Molecular Formula Fragments

  • C30-H35-N-O11
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C30H35NO11.ClH/c1-3-30(39)12-17(42-18-11-15(24(33)13(2)41-18)31-7-9-40-10-8-31)20-23(29(30)38)28(37)21-22(27(20)36)26(35)19-14(25(21)34)5-4-6-16(19)32;/h4-6,13,15,17-18,24,29,32-33,36-39H,3,7-12H2,1-2H3;1H

InChIKey

ZDJRSUWWMAYYID-UHFFFAOYSA-N

Smiles

N1([C@@H]2C[C@@H](O[C@@H]([C@@H]2O)C)O[C@@H]2c3c(O)c4C(=O)c5c(cccc5C(=O)c4c(c3[C@@H]([C@@](C2)(O)CC)O)O)O)CCOCC1.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 4930ug/kg (4.93mg/kg)   Cancer Research. Vol. 49, Pg. 4098, 1989.
rat LDLo intraarterial 3mg/kg (3mg/kg) BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES Gan to Kagaku Ryoho. Cancer and Chemotherapy. Vol. 18, Pg. 371, 1991.
rat LDLo intravenous 3mg/kg (3mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BLOOD: HEMORRHAGE
Gan to Kagaku Ryoho. Cancer and Chemotherapy. Vol. 18, Pg. 371, 1991.