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Substance Name: Vamicamide [INN]
RN: 132373-81-0
UNII: RU10K34QRU
InChIKey: BWNLUIXQIHPUGO-RDTXWAMCSA-N

Note

  • A potent anticholinergic drug.

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C18-H23-N3-O

Molecular Weight

  • 297.4
 
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Names and Synonyms

Name of Substance

  • Vamicamide (+-)-
  • Vamicamide [INN]

Synonyms

  • (+-)-(2R*,4R*)-4-Dimethylamino-2-phenyl-2-(2-pyridyl)valeramide
  • (+-)-(R*)-alpha-((R*)-2-(Dimethylamino)propyl)-alpha-phenyl-2-pyridineacetamide
  • (R*,R*)-(+-)-alpha-(2-(Dimethylamino)propyl)-alpha-phenyl-2-pyridineacetmide
  • UNII-RU10K34QRU
  • Vamicamide

Systematic Names

  • (+-)-(R*)-alpha-((R*)-2-(Dimethylamino)propyl)-alpha-phenyl-2-pyridineacetamide
  • 2-Pyridineacetamide, alpha-(2-(dimethylamino)propyl)-alpha-phenyl-, (R*,R*)-(+-)-

Registry Numbers

CAS Registry Number

  • 132373-81-0

FDA UNII

  • RU10K34QRU

System Generated Number

  • 0132373810

Structure Descriptors

InChI

1S/C18H23N3O/c1-14(21(2)3)13-18(17(19)22,15-9-5-4-6-10-15)16-11-7-8-12-20-16/h4-12,14H,13H2,1-3H3,(H2,19,22)/t14-,18-/m1/s1

InChIKey

BWNLUIXQIHPUGO-RDTXWAMCSA-N

Smiles

c1(ccccn1)[C@](C(N)=O)(c1ccccc1)C[C@H](N(C)C)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LD50 intravenous 42300ug/kg (42.3mg/kg)   United States Patent Document. Vol. #5202331,
rat LD50 subcutaneous 915mg/kg (915mg/kg)   United States Patent Document. Vol. #5202331,