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Substance Name: Lesopitron dihydrochloride
RN: 132449-89-9
UNII: 4T5L4T8473
InChIKey: RGDLQJUAYQRGBC-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C15-H21-Cl-N6.2Cl-H

Molecular Weight

  • 393.748
 
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Names and Synonyms

Name of Substance

  • E 4424
  • Lesopitron dihydrochloride

Synonyms

  • 2-(4-(4-(4-Chloro-1H-pyrazol-1-yl)butyl)-1-piperazinyl)pyrimidine dihydrochloride
  • E 4424
  • Lesopitron dihydrochloride
  • UNII-4T5L4T8473

Systematic Name

  • Pyrimidine, 2-(4-(4-(4-chloro-1H-pyrazol-1-yl)butyl)-1-piperazinyl)-, dihydrochloride

Registry Numbers

CAS Registry Number

  • 132449-89-9

FDA UNII

  • 4T5L4T8473

System Generated Number

  • 0132449899

Molecular Formulas

Molecular Formula

  • C15-H21-Cl-N6.2Cl-H

Molecular Formula Fragments

  • C15-H21-Cl-N6
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C15H21ClN6.2ClH/c16-14-12-19-22(13-14)7-2-1-6-20-8-10-21(11-9-20)15-17-4-3-5-18-15;;/h3-5,12-13H,1-2,6-11H2;2*1H

InChIKey

RGDLQJUAYQRGBC-UHFFFAOYSA-N

Smiles

N1(c2ncccn2)CCN(CCCCn2cc(Cl)cn2)CC1.Cl.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 230mg/kg (230mg/kg)   Drugs of the Future. Vol. 19, Pg. 651, 1994.
mouse LD50 oral 680mg/kg (680mg/kg)   Drugs of the Future. Vol. 19, Pg. 651, 1994.
rat LD50 intraperitoneal 131mg/kg (131mg/kg)   Drugs of the Future. Vol. 19, Pg. 651, 1994.
rat LD50 oral 374mg/kg (374mg/kg)   Drugs of the Future. Vol. 19, Pg. 651, 1994.