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Substance Name: Meglumine antimoniate
RN: 133-51-7
UNII: 75G4TW236W
InChIKey: XOGYVDXPYVPAAQ-SESJOKTNSA-M

Note

  • Used in treatment of leishmaniasis.

Molecular Formula

  • C7-H17-N-O5.H.O3-Sb

Molecular Weight

  • 365.9782
 

Classification Codes

  • Anti-Infective Agents
  • Antiparasitic Agents
  • Antiprotozoal Agents
  • Drug / Therapeutic Agent
  • Human Data
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Names and Synonyms

Name of Substance

  • Meglumine antimoniate

Synonyms

  • 2168-RP
  • D-Glucitol, 1-deoxy-1-(methylamino)-, compd. with antimonic acid (1:1)
  • EINECS 205-108-3
  • Glucantime
  • Glucitol, 1-deoxy-1-(methylamino)-, compd. with antimonic acid (1:1), D-
  • Meglumine antimonate
  • Methylglucamine antimonate
  • N-Methylglucamine antimonate
  • Protostib
  • UNII-75G4TW236W

Systematic Names

  • 1-Deoxy-1-(methylamino)-D-glucitol, compound with antimonic acid (1:1)
  • 1-Deoxy-1-(methylamino)glucitol antimonate(V)
  • D-Glucitol, 1-deoxy-1-(methylamino)-, trioxoantimonate(1-)

Registry Numbers

CAS Registry Number

  • 133-51-7

FDA UNII

  • 75G4TW236W

System Generated Number

  • 0000133517

Molecular Formulas

Molecular Formula

  • C7-H17-N-O5.H.O3-Sb

Molecular Formula Fragments

  • C7-H17-N-O5
  • COMPONENT
  • H
  • O3-Sb

Structure Descriptors

InChI

1S/C7H17NO5.H2O.2O.Sb/c1-8-2-4(10)6(12)7(13)5(11)3-9;;;;/h4-13H,2-3H2,1H3;1H2;;;/q;;;;+1/p-1/t4-,5+,6+,7+;;;;/m0..../s1

InChIKey

XOGYVDXPYVPAAQ-SESJOKTNSA-M

Smiles

CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O.O[Sb](=O)=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
child TDLo unreported 700mg/kg/7D (700mg/kg) KIDNEY, URETER, AND BLADDER: INTERSTITIAL NEPHRITIS

KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED

KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED
Maroc Medical. Vol. 41, Pg. 1180, 1962.