Substance Name: Asbestos
RN: 1332-21-4
Notes
- Asbestos. Fibrous incombustible mineral composed of magnesium and calcium silicates with or without other elements. It is relatively inert chemically and used in thermal insulation and fireproofing. Inhalation of dust causes asbestosis and later lung and gastrointestinal neoplasms.
- TSCA Definition 2022: A grayish, noncombustible fibrous material. It consists primarily of impure magnesium silicate minerals.
Molecular Formula
- Unspecified
Classification Codes
Classification Codes
- Carcinogens
- Human Data
- Mutation Data
- Natural Product
- Noxae
- TSCA Flag R (Subject to the TSCA Section 6 Risk Management Rule)
- TSCA Flag S (Substance is Identified in a Final Significant New Use Rule)
- TSCA UVCB
- Tumor Data
Superlist Classification Codes
- 2007 CERCLA Priority List, Rank: 90
- 2011 CERCLA Priority List, Rank: 94
- Known to be a Carcinogen
- Overall Carcinogenic Evaluation: Group 1
- Reportable Quantity (RQ) = 1 lb
- TWA 0.1 f/cc (longer than 5 um); Confirmed human carcinogen
- TWA see 1910.1001
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Links to Resources
NLM Resources (File Locators)
Regulatory Agencies (Superlist Locators)
Other Resources (Internet Locators)
Names and Synonyms
Name of Substance
- Asbestos
MeSH Heading
- Asbestos
Synonyms
- Amianthus
- Asbest
- Asbest [German]
- Asbestos
- Asbestos dust
- Asbestos fiber
- Asbestos fibers
- Asbestos fibre
- Asbestose
- Asbestose [German]
- Ascarite
- AT 7-1
- BK 6-20
- BP 3-50
- BP 5-65
- Calidria HPP
- Calidria R-G 244
- Carey 4T
- Caswell No. 061
- CCRIS 56
- Chlorobestos 25
- EPA Pesticide Chemical Code 099301
- FAPM 410-120
- Ferodo C3C
- Fibrous grunerite
- HPO (mineral)
- HSDB 511
- K 6-20
- M 3-60
- M 4-5
- M 5-60
- M 6-40
- Mountain cork
- Mountain leather
- Mountain wood
- MTM
- NCI C08991
- P 5-50
- P 5-50 (mineral)
- Sepiolex 3
- Sepiolex 5
- SM 1 (mineral)
- SM 2 (mineral)
Systematic Name
- Asbestos
Superlist Names
- Asbestos
- Asbestos (friable)
- Asbestos, all forms
- Man-made mineral fibres
Registry Numbers
CAS Registry Number
- 1332-21-4
Other Registry Numbers
- 12413-45-5
- 329202-13-3
- 77641-59-9
System Generated Number
- 0001332214
Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| human | TCLo | inhalation | 1.2fb/cc/19Y- (1.2fb/cc) | LUNGS, THORAX, OR RESPIRATION: PLEURAL EFFUSION LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: SPUTUM | American Review of Respiratory Disease. Vol. 104, Pg. 576, 1971. |
| rat | LD | intratracheal | > 4mL/kg (4mL/kg) | LUNGS, THORAX, OR RESPIRATION: STRUCTURAL OR FUNCTIONAL CHANGE IN TRACHEA OR BRONCHI LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Zhonghua Yufangyixue Zazhi. Chinese Journal of Preventive Medicine. Vol. 32, Pg. 139, 1998. |