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Substance Name: Chromic trioxide
RN: 1333-82-0
UNII: 8LV49809UC
InChIKey: WGLPBDUCMAPZCE-UHFFFAOYSA-N

Note

  • Oxidizing agent.

Molecular Formula

  • Cr-O3

Molecular Weight

  • 99.993
 

Classification Codes

Classification Codes

  • Human Data
  • Indicators and Reagents
  • Mutation Data
  • Reproductive Effect
  • TSCA Flag R (Subject to a Section 6 Risk Management Rule under TSCA)
  • Tumor Data

Superlist Classification Codes

  • 2007 CERCLA Priority List, Rank: 65
  • 2011 CERCLA Priority List, Rank: 66
  • Known to be a Carcinogen

Names and Synonyms

Name of Substance

  • Chromic trioxide
  • Chromium trioxide

Synonyms

  • Anhydride chromique
  • Anhydride chromique [French]
  • Anidride cromica
  • Anidride cromica [Italian]
  • CCRIS 160
  • Chrome (trioxyde de)
  • Chrome (trioxyde de) [French]
  • Chromia (CrO3)
  • Chromic acid, solid
  • Chromic anhydride
  • Chromic oxide
  • Chromic(VI) acid
  • Chromium oxide
  • Chromium oxide (Cr4O12)
  • Chromium oxide (CrO3)
  • Chromium trioxide
  • Chromium(6+) oxide
  • Chromium(6+) trioxide
  • Chromium(VI) oxide
  • Chromium(VI) trioxide
  • Chromsaeureanhydrid
  • Chromsaeureanhydrid [German]
  • Chromtrioxid
  • Chromtrioxid [German]
  • Chroomtrioxyde
  • Chroomtrioxyde [Dutch]
  • Chroomzuuranhydride
  • Chroomzuuranhydride [Dutch]
  • Cromo(triossido di)
  • Cromo(triossido di) [Italian]
  • EC 215-607-8
  • EINECS 215-607-8
  • HSDB 518
  • Monochromium trioxide
  • Puratronic chromium trioxide
  • Sintered chromium trioxide
  • UNII-8LV49809UC

Systematic Names

  • Chromium oxide (CrO3)
  • Chromium trioxide
  • Chromium trioxide, sintered
  • Chromium(VI) oxide (1:3)

Superlist Names

  • Chromium anhydride
  • Chromium oxide
  • Chromium trioxide [Chromium and chromium compounds]
  • Chromium trioxide, anhydrous
  • Chromium trioxide, anhydrous [UN1463] [Oxidizer]
  • Chromium(VI) oxide
  • Chromium(VI) trioxide
  • UN1463

Registry Numbers

CAS Registry Number

  • 1333-82-0

FDA UNII

  • 8LV49809UC

Other Registry Numbers

  • 12324-05-9
  • 12324-08-2

System Generated Number

  • 0001333820

Structure Descriptors

InChI

1S/Cr.3O

InChIKey

WGLPBDUCMAPZCE-UHFFFAOYSA-N

Smiles

[Cr](=O)(=O)=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
human TCLo inhalation 110ug/m3 (0.11mg/m3)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 22, Pg. 291, 1980.
mouse LD50 intraperitoneal 14mg/kg (14mg/kg)   Nippon Eiseigaku Zasshi. Japanese Journal of Hygiene. Vol. 34, Pg. 193, 1979.
mouse LD50 intravenous 17100ug/kg (17.1mg/kg)   Indian Journal of Pharmacology. Vol. 23, Pg. 153, 1991.
mouse LD50 oral 127mg/kg (127mg/kg)   Zhonghua Yufangyixue Zazhi. Chinese Journal of Preventive Medicine. Vol. 14, Pg. 86, 1980.
mouse LDLo subcutaneous 20mg/kg (20mg/kg)   Senten Ijo. Congenital Anomalies. Vol. 19, Pg. 171, 1979.
rat LD50 intraperitoneal 58400ug/kg (58.4mg/kg)   Indian Journal of Pharmacology. Vol. 23, Pg. 153, 1991.
rat LD50 intravenous 9260ug/kg (9.26mg/kg)   Indian Journal of Pharmacology. Vol. 23, Pg. 153, 1991.
rat LD50 oral 80mg/kg (80mg/kg) LUNGS, THORAX, OR RESPIRATION: CYANOSIS

SKIN AND APPENDAGES (SKIN): HAIR: OTHER

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research Laboratory of Public Health. Vol. 27, Pg. 119, 1976.
rat LDLo skin 55mg/kg (55mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"

BEHAVIORAL: FOOD INTAKE (ANIMAL)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
National Technical Information Service. Vol. OTS0537097,