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Substance Name: Lactacystin
RN: 133343-34-7
InChIKey: DAQAKHDKYAWHCG-RWTHQLGUSA-N

Note

  • From a Streptomyces strain; induces neuritogenesis of neuroblastoma cells.

Classification Codes

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Cysteine Proteinase Inhibitors
  • Enzyme Inhibitors
  • Protease Inhibitors

Molecular Formula

  • C15-H24-N2-O7-S

Molecular Weight

  • 376.4276
 
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Names and Synonyms

Name of Substance

  • Lactacystin

Systematic Names

  • L-Cysteine, N-acetyl-, (2R,3S,4R)-3-hydroxy-2-(1-hydroxy-2-methylpropyl)-4-methyl-5-oxo-2-pyrrolidinecarboxylate (ester)
  • L-Cysteine, N-acetyl-, 3-hydroxy-2-(1-hydroxy-2-methylpropyl)-4-methyl-5-oxo-2-pyrrolidinecarboxylate (ester), (2R-(2alpha,2(S*),3alpha,4alpha))-

Registry Numbers

CAS Registry Number

  • 133343-34-7

System Generated Number

  • 0133343347

Structure Descriptors

InChI

1S/C15H24N2O7S/c1-6(2)10(19)15(11(20)7(3)12(21)17-15)14(24)25-5-9(13(22)23)16-8(4)18/h6-7,9-11,19-20H,5H2,1-4H3,(H,16,18)(H,17,21)(H,22,23)/t7-,9+,10+,11+,15-/m1/s1

InChIKey

DAQAKHDKYAWHCG-RWTHQLGUSA-N

Smiles

C(=O)(SC[C@H](NC(C)=O)C(O)=O)[C@@]1([C@H]([C@H](C(N1)=O)C)O)[C@H](C(C)C)O