Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Peldesine [USAN:INN]
RN: 133432-71-0
UNII: 7B646RJ70F
InChIKey: DOHVAKFYAHLCJP-UHFFFAOYSA-N

Note

  • Potent inhibitor of human CCRF-CEM T-cell proliferation.

Molecular Formula

  • C12-H11-N5-O

Molecular Weight

  • 241.253
 

Classification Codes

  • Antineoplastic
  • Antipsoriatic
  • Drug / Therapeutic Agent
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Peldesine
  • Peldesine [USAN:INN]

Synonyms

  • 2-Amino-3,5-dihydro-7-(3-pyridylmethyl)-4H-pyrrolo(3,2-d)pyrimidin-4-one
  • 9-(3-Pyridylmethyl)-7H-9-deazaguanine
  • BCX-34
  • Peldesine
  • UNII-7B646RJ70F

Systematic Name

  • 4H-Pyrrolo(3,2-d)pyrimidin-4-one, 2-amino-3,5-dihydro-7-(3-pyridinylmethyl)-

Registry Numbers

CAS Registry Number

  • 133432-71-0

FDA UNII

  • 7B646RJ70F

System Generated Number

  • 0133432710

Structure Descriptors

InChI

1S/C12H11N5O/c13-12-16-9-8(4-7-2-1-3-14-5-7)6-15-10(9)11(18)17-12/h1-3,5-6,15H,4H2,(H3,13,16,17,18)

InChIKey

DOHVAKFYAHLCJP-UHFFFAOYSA-N

Smiles

c12c(Cc3cccnc3)c[nH]c1c([nH]c(n2)N)=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD intravenous > 88mg/kg (88mg/kg)   Drugs of the Future. Vol. 18, Pg. 887, 1993.
mouse LD oral > 3gm/kg (3000mg/kg)   Drugs of the Future. Vol. 18, Pg. 887, 1993.
rabbit LD intravenous > 100mg/kg (100mg/kg)   Drugs of the Future. Vol. 18, Pg. 887, 1993.