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Substance Name: 1-Naphthylamine
RN: 134-32-7
UNII: 9753I242R5
InChIKey: RUFPHBVGCFYCNW-UHFFFAOYSA-N

Note

  • A suspected industrial carcinogen (and listed as such by OSHA). Its N-hydroxy metabolite is strongly carcinogenic and mutagenic.

Molecular Formula

  • C10-H9-N

Molecular Weight

  • 143.1881
 

Classification Codes

Classification Codes

  • Carcinogens
  • Mutation Data
  • Noxae
  • Tumor Data

Superlist Classification Codes

  • Overall Carcinogenic Evaluation: Group 3
  • Reportable Quantity (RQ) = 100 lb
  • TWA see 1910.1004

Names and Synonyms

Name of Substance

  • 1-Naphthylamine

MeSH Heading

  • 1-Naphthylamine

Synonyms

  • 1-Aminonaftalen
  • 1-Aminonaftalen [Czech]
  • 1-Aminonaphthalene
  • 1-Naftilamina
  • 1-Naftilamina [Spanish]
  • 1-Naftylamin
  • 1-Naftylamin [Czech]
  • 1-Naftylamine
  • 1-Naftylamine [Dutch]
  • 1-Naphthalamine
  • 1-Naphthalenamine
  • 1-Naphthylamin
  • 1-Naphthylamin [German]
  • 1-Naphthylamine
  • 1-Naphthylamine, technical grade
  • 4-12-00-03009 (Beilstein Handbook Reference)
  • AI3-00085
  • alfa-Naftyloamina
  • alfa-Naftyloamina [Polish]
  • Alfanaftilamina
  • Alfanaftilamina [Italian]
  • alpha-Aminonaphthalene
  • alpha-Naftalamin
  • alpha-Naftalamin [Czech]
  • alpha-Naftylamin
  • alpha-Naftylamin [Czech]
  • alpha-Naphthylamine
  • BRN 0386133
  • C.I. Azoic Diazo Component 114
  • CCRIS 423
  • CI 37265
  • CI Azoic Diazo Component 114
  • EC 205-138-7
  • EINECS 205-138-7
  • Fast Garnet B Base
  • Fast Garnet Base B
  • HSDB 1080
  • Naphthalidam
  • Naphthalidine
  • RCRA waste number U167
  • UNII-9753I242R5

Systematic Names

  • 1-Naphthalenamine
  • 1-Naphthylamine

Superlist Names

  • 1-Naphthalenamine
  • 1-Naphthylamine
  • alpha-Naphthylamine
  • alpha-Naphthylamine [UN2077] [Poison]
  • RCRA waste no. U167
  • UN2077

Registry Numbers

CAS Registry Number

  • 134-32-7

FDA UNII

  • 9753I242R5

Other Registry Number

  • 12262-09-8

System Generated Number

  • 0000134327

Structure Descriptors

InChI

1S/C10H9N/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7H,11H2

InChIKey

RUFPHBVGCFYCNW-UHFFFAOYSA-N

Smiles

c12c(c(ccc1)N)cccc2

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mammal (species unspecified) LDLo oral 4gm/kg (4000mg/kg)   Journal of Industrial Hygiene. Vol. 13, Pg. 87, 1931.
mouse LD50 intraperitoneal 96mg/kg (96mg/kg)   Progress in Mutation Research. Vol. 1, Pg. 682, 1981.
rabbit LDLo subcutaneous 300mg/kg (300mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: TREMOR
U.S. Public Health Service, Public Health Bulletin. Vol. 271, Pg. 174, 1941.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 49.2 deg C   EXP
Boiling Point 300.8 deg C   EXP
pKa Dissociation Constant 3.92 (none) 25 EXP
log P (octanol-water) 2.25 (none)   EXP
Water Solubility 1700 mg/L 20 EXP
Henry's Law Constant 1.11E-07 atm-m3/mole 25 EXP
Atmospheric OH Rate Constant 2.00E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.