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Substance Name: Amphenidone [INN]
RN: 134-37-2
UNII: M61FM2VCSV
InChIKey: ZVSGUZQJNXHNIL-UHFFFAOYSA-N

Classification Code

  • Tranquilizer

Molecular Formula

  • C11-H10-N2-O

Molecular Weight

  • 186.213
 
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Names and Synonyms

Name of Substance

  • Amphenidone
  • Amphenidone [INN]

Synonyms

  • 1-(3-Aminophenyl)-2-(1H)-pyridinone
  • 1-(3-Aminophenyl)-2-pyridone
  • 1-(m-Aminofenylo)-2-pirydonu
  • 1-(m-Aminofenylo)-2-pirydonu [Polish]
  • 1-(m-Aminophenyl)-2(1H)-pyridone
  • 1-m-Aminophenyl-2-pyridone
  • 5-21-07-00122 (Beilstein Handbook Reference)
  • Amfenidona
  • Amfenidona [INN-Spanish]
  • Aminophenylpyridone
  • Amphenidone
  • Amphenidonum
  • Amphenidonum [INN-Latin]
  • BRN 1526918
  • Dornwal
  • UNII-M61FM2VCSV

Systematic Names

  • 1-(m-Aminophenyl)-2(1H)-pyridone
  • 2(1H)-Pyridone, 1-(m-aminophenyl)-

Registry Numbers

CAS Registry Number

  • 134-37-2

FDA UNII

  • M61FM2VCSV

System Generated Number

  • 0000134372

Structure Descriptors

InChI

1S/C11H10N2O/c12-9-4-3-5-10(8-9)13-7-2-1-6-11(13)14/h1-8H,12H2

InChIKey

ZVSGUZQJNXHNIL-UHFFFAOYSA-N

Smiles

c1(n2c(cccc2)=O)cc(ccc1)N

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 600mg/kg (600mg/kg)   Acta Poloniae Pharmaceutica. For English translation, see APPFAR. Vol. 20, Pg. 155, 1963.
mouse LD50 intravenous 565mg/kg (565mg/kg)   Acta Poloniae Pharmaceutica. For English translation, see APPFAR. Vol. 20, Pg. 155, 1963.
mouse LD50 oral 1300mg/kg (1300mg/kg) BEHAVIORAL: SLEEP

BEHAVIORAL: ATAXIA

BEHAVIORAL: MUSCLE WEAKNESS
Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 19, Pg. 390, 1960.
rat LD50 oral 2300mg/kg (2300mg/kg) BEHAVIORAL: SLEEP

BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: ATAXIA
Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 19, Pg. 390, 1960.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 183 deg C   EXP
log P (octanol-water) 0.450 (none)   EST
Atmospheric OH Rate Constant 2.30E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.