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Substance Name: Dexelvucitabine [USAN:INN]
RN: 134379-77-4
UNII: KU8SPJ271W
InChIKey: HSBKFSPNDWWPSL-CAHLUQPWSA-N

Note

  • Inhibits human hepatitis B virus (HBV) and human immunodeficiency virus (HIV) in vitro; D4FC-TP is the triphosphate form.

Molecular Formula

  • C9-H10-F-N3-O3

Molecular Weight

  • 227.194
 

Classification Codes

  • Anti-HIV Agents
  • Anti-Infective Agents
  • Anti-Retroviral Agents
  • Antiviral
  • Antiviral Agents
  • Enzyme Inhibitors
  • Nucleic Acid Synthesis Inhibitors
  • Reverse Transcriptase Inhibitors
  • Treatment of HIV-1 and HIV-2 Infection
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Names and Synonyms

Name of Substance

  • Dexelvucitabine
  • Dexelvucitabine [USAN:INN]

Synonyms

  • 2',3'-Didehydro-2',3'-dideoxy-5-fluorocytidine
  • 2',3'-Dideoxy-2',3'-didehydro-beta-L-5-fluorocytidine
  • D-d4FC
  • Dexelvucitabine
  • DOC 817
  • DPC 817
  • DPC-817
  • INCB 8721
  • INCB-8721
  • RA 131423
  • Reverset
  • UNII-KU8SPJ271W
  • YZ 817
  • YZ-817

Systematic Names

  • ( )-4-amino-5-fluoro-1-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl)pyrimidin-2(1H)-one
  • Cytidine, 2',3'-didehydro-2',3'-dideoxy-5-fluoro-

Registry Numbers

CAS Registry Number

  • 134379-77-4

FDA UNII

  • KU8SPJ271W

System Generated Number

  • 0134379774

Structure Descriptors

InChI

1S/C9H10FN3O3/c10-6-3-13(9(15)12-8(6)11)7-2-1-5(4-14)16-7/h1-3,5,7,14H,4H2,(H2,11,12,15)/t5-,7+/m0/s1

InChIKey

HSBKFSPNDWWPSL-CAHLUQPWSA-N

Smiles

c1c(c(nc(=O)n1[C@H]2C=C[C@H](O2)CO)N)F