Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Clorotepine [INN]
RN: 13448-22-1
UNII: E65W20MU7A
InChIKey: XRYLGRGAWQSVQW-UHFFFAOYSA-N

Note

  • Major tranquilizer with action similar to those of the phenothiazines; used in schizophrenic & manic psychoses.

Molecular Formula

  • C19-H21-Cl-N2-S

Molecular Weight

  • 344.9079
 

Classification Codes

  • Drug / Therapeutic Agent
  • Reproductive Effect
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Clorotepine [INN]
  • Octoclothepine

Synonyms

  • 1-(8-Chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-4-methylpiperazine
  • Clorotepina
  • Clorotepina [INN-Spanish]
  • Clorotepine
  • Clorotepinum
  • Clorotepinum [INN-Latin]
  • Clotepin
  • Clothepin
  • Octoclothepin
  • Octoclothepine
  • UNII-E65W20MU7A

Systematic Names

  • 1-(8-Chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-4-methylpiperazine
  • Piperazine, 1-(8-chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-4-methyl-

Registry Numbers

CAS Registry Number

  • 13448-22-1

FDA UNII

  • E65W20MU7A

Related Registry Numbers

  • 42505-79-3 (monomethanesulfonate salt)
  • 4789-68-8 (2-maleate salt)

System Generated Number

  • 0013448221

Structure Descriptors

InChI

1S/C19H21ClN2S/c1-21-8-10-22(11-9-21)17-12-14-4-2-3-5-18(14)23-19-7-6-15(20)13-16(17)19/h2-7,13,17H,8-12H2,1H3

InChIKey

XRYLGRGAWQSVQW-UHFFFAOYSA-N

Smiles

CN1CCN(CC1)C2Cc3ccccc3Sc4c2cc(cc4)Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 78mg/kg (78mg/kg) BEHAVIORAL: ATAXIA Collection of Czechoslovak Chemical Communications. Vol. 48, Pg. 144, 1983.