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Substance Name: Atorvastatin [INN:BAN]
RN: 134523-00-5
UNII: A0JWA85V8F
InChIKey: XUKUURHRXDUEBC-KAYWLYCHSA-N

Note

  • Hydroxymethylglutaryl-CoA reductase inhibitor.

Molecular Formula

  • C33-H35-F-N2-O5

Molecular Weight

  • 558.6465
 

Classification Codes

  • Anticholesteremic Agents
  • Antimetabolites
  • Enzyme Inhibitors
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Hypolipidemic Agents
  • Lipid Regulating Agents

Names and Synonyms

Name of Substance

  • Atorvastatin
  • Atorvastatin [INN:BAN]

Synonyms

  • (betaR,deltaR)-2-(p-Fluorophenyl)-beta,delta-dihydroxy-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoic acid
  • (R-(R*,R*))-2-(4-Fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-1H-pyrrole-1-heptanoic acid
  • Atofast
  • Ator
  • Atorcor
  • Atorin
  • Atorvastatin
  • Cardyl
  • CCRIS 7159
  • HSDB 7039
  • Lipilou
  • Lipinon
  • Torvast
  • Tozalip
  • UNII-A0JWA85V8F
  • Xavator

Systematic Names

  • 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-, (betaR,deltaR)-
  • 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-, (R-(R*,R*))-

Registry Numbers

CAS Registry Number

  • 134523-00-5

FDA UNII

  • A0JWA85V8F

System Generated Number

  • 0134523005

Structure Descriptors

InChI

1S/C33H35FN2O5/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40)/t26-,27-/m1/s1

InChIKey

XUKUURHRXDUEBC-KAYWLYCHSA-N

Smiles

CC(C)c1c(C(=O)Nc2ccccc2)c(c3ccccc3)c(c4ccc(F)cc4)n1CC[C@@H](O)C[C@@H](O)CC(=O)O

Physical Properties

Physical Property Value Units Temp (deg C) Source
log P (octanol-water) 6.360 (none)   EST
Atmospheric OH Rate Constant 2.28E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.