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Substance Name: Leucinocaine mesylate
RN: 135-44-4
UNII: 72E501K01E

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C17-H28-N2-O2.C-H4-O3-S

Molecular Weight

  • 388.526
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Names and Synonyms

Name of Substance

  • Leucinocaine mesylate


  • 2-(Diethylamino)-4-methyl-1-pentanol, p-aminobenzoate ester, methanesulfonate
  • 2-Methyl-4-diethylaminopentan-5-ol p-aminobenzoate
  • EINECS 205-191-6
  • Leucinocaine mesylate
  • Leucinocaine methanesulfonate
  • Methanesulfonic acid, compd. with 2-(diethylamino)-4-methylpentyl P-aminobenzoate (1:1)
  • N,N-Diethylleucinon-p-aminobenzoic acid methanesulfonate
  • p-Aminobenzoic acid beta-diethylaminoisohexyl ester methanesulfonate
  • p-Aminobenzoic acid N,N-diethylleucinol ester methanesulfonate
  • p-Aminobenzoic acid-N-1-diethylamino-1-isobutylethanol methanesulfonate
  • Panthesin
  • Panthesine
  • S.P. 147
  • UNII-72E501K01E

Systematic Names

  • 1-Pentanol, 2-(diethylamino)-4-methyl-, p-aminobenzoate (ester), monomethanesulfonate
  • 2-(Diethylamino)-4-methylpentyl 4-aminobenzoate, monomethanesulphonate

Registry Numbers

CAS Registry Number

  • 135-44-4


  • 72E501K01E

System Generated Number

  • 0000135444

Molecular Formulas

Molecular Formula

  • C17-H28-N2-O2.C-H4-O3-S

Molecular Formula Fragments

  • C-H4-O3-S
  • C17-H28-N2-O2

Structure Descriptors








Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LDLo intravenous 20mg/kg (20mg/kg)   Physiological Reviews. Vol. 12, Pg. 190, 1932.
guinea pig LDLo subcutaneous 112mg/kg (112mg/kg)   Physiological Reviews. Vol. 12, Pg. 190, 1932.
mouse LDLo intravenous 49mg/kg (49mg/kg) BEHAVIORAL: GENERAL ANESTHETIC "Vergleichend-pharmakologische Untersuchungen ueber die haemolytische Wirkung und die Toxizitat der Lokalanaesthetika, Dissertation," Walther, M., Pharmakologischen Instit Martin Luther-Universitat Halle-Wittenburg, Ger. Dem. Rep., 1936Vol. -, Pg. -, 1936.
mouse LDLo subcutaneous 300mg/kg (300mg/kg)   Physiological Reviews. Vol. 12, Pg. 190, 1932.
rabbit LDLo intraspinal 10200ug/kg (10.2mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 54, Pg. 137, 1935.
rabbit LDLo intravenous 20mg/kg (20mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 57, Pg. 221, 1936.
rabbit LDLo subcutaneous 240mg/kg (240mg/kg)   Physiological Reviews. Vol. 12, Pg. 190, 1932.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 158 deg C   EXP
log P (octanol-water) 3.800 (none)   EST
Atmospheric OH Rate Constant 1.52E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.