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Substance Name: Leucinocaine mesylate
RN: 135-44-4
UNII: 72E501K01E
InChIKey: RFPVXZWXDPIKSD-UHFFFAOYSA-N
Classification Code
- Drug / Therapeutic Agent
Molecular Formula
- C17-H28-N2-O2.C-H4-O3-S
Molecular Weight
- 388.526
- All
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Formulas
- Structure Descriptors
- Toxicity
- Physical Properties
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Names and Synonyms
Name of Substance
- Leucinocaine mesylate
Synonyms
- 2-(Diethylamino)-4-methyl-1-pentanol, p-aminobenzoate ester, methanesulfonate
- 2-Methyl-4-diethylaminopentan-5-ol p-aminobenzoate
- EINECS 205-191-6
- Leucinocaine mesylate
- Leucinocaine methanesulfonate
- Methanesulfonic acid, compd. with 2-(diethylamino)-4-methylpentyl P-aminobenzoate (1:1)
- N,N-Diethylleucinon-p-aminobenzoic acid methanesulfonate
- p-Aminobenzoic acid beta-diethylaminoisohexyl ester methanesulfonate
- p-Aminobenzoic acid N,N-diethylleucinol ester methanesulfonate
- p-Aminobenzoic acid-N-1-diethylamino-1-isobutylethanol methanesulfonate
- Panthesin
- Panthesine
- S.P. 147
- UNII-72E501K01E
Systematic Names
- 1-Pentanol, 2-(diethylamino)-4-methyl-, p-aminobenzoate (ester), monomethanesulfonate
- 2-(Diethylamino)-4-methylpentyl 4-aminobenzoate, monomethanesulphonate
Registry Numbers
CAS Registry Number
- 135-44-4
FDA UNII
- 72E501K01E
System Generated Number
- 0000135444
Molecular Formulas
Molecular Formula
- C17-H28-N2-O2.C-H4-O3-S
Molecular Formula Fragments
- C-H4-O3-S
- C17-H28-N2-O2
- COMPONENT
Structure Descriptors
InChI
1S/C17H28N2O2.CH4O3S/c1-5-19(6-2)16(11-13(3)4)12-21-17(20)14-7-9-15(18)10-8-14;1-5(2,3)4/h7-10,13,16H,5-6,11-12,18H2,1-4H3;1H3,(H,2,3,4)InChIKey
RFPVXZWXDPIKSD-UHFFFAOYSA-NSmiles
C(OC[C@@H](N(CC)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LDLo | intravenous | 20mg/kg (20mg/kg) | Physiological Reviews. Vol. 12, Pg. 190, 1932. | |
guinea pig | LDLo | subcutaneous | 112mg/kg (112mg/kg) | Physiological Reviews. Vol. 12, Pg. 190, 1932. | |
mouse | LDLo | intravenous | 49mg/kg (49mg/kg) | BEHAVIORAL: GENERAL ANESTHETIC | "Vergleichend-pharmakologische Untersuchungen ueber die haemolytische Wirkung und die Toxizitat der Lokalanaesthetika, Dissertation," Walther, M., Pharmakologischen Instit Martin Luther-Universitat Halle-Wittenburg, Ger. Dem. Rep., 1936Vol. -, Pg. -, 1936. |
mouse | LDLo | subcutaneous | 300mg/kg (300mg/kg) | Physiological Reviews. Vol. 12, Pg. 190, 1932. | |
rabbit | LDLo | intraspinal | 10200ug/kg (10.2mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 54, Pg. 137, 1935. | |
rabbit | LDLo | intravenous | 20mg/kg (20mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 57, Pg. 221, 1936. | |
rabbit | LDLo | subcutaneous | 240mg/kg (240mg/kg) | Physiological Reviews. Vol. 12, Pg. 190, 1932. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 158 | deg C | EXP | |
log P (octanol-water) | 3.800 | (none) | EST | |
Atmospheric OH Rate Constant | 1.52E-10 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.