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Substance Name: Poststatin
RN: 135219-43-1
InChIKey: UNPBSZUDTFBULK-CZCKBYKRSA-N

Note

  • Inhibitor of prolyl endopeptidase; produced by Streptomyces viridochromogenes MH534-30F3.

Classification Codes

  • Drug / Therapeutic Agent
  • Natural Product

Molecular Formula

  • C26-H47-N5-O7

Molecular Weight

  • 541.685
 
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Names and Synonyms

Name of Substance

  • Poststatin

Synonym

  • L-Valine, L-valyl-L-valyl-2-oxo-L-3-aminopentanoyl-D-leucyl-

Systematic Names

  • L-Valine, L-valyl-L-valyl-2-oxo-L-3-aminopentanoyl-D-leucyl-
  • Poststatin

Registry Numbers

CAS Registry Number

  • 135219-43-1

System Generated Number

  • 0135219431

Structure Descriptors

InChI

1S/C26H47N5O7/c1-9-16(27)22(33)23(34)30-17(10-12(2)3)24(35)31(21(14(6)7)26(37)38)25(36)20(29)15(8)11-18(32)19(28)13(4)5/h12-17,19-21H,9-11,27-29H2,1-8H3,(H,30,34)(H,37,38)/t15?,16-,17+,19-,20-,21-/m0/s1

InChIKey

UNPBSZUDTFBULK-CZCKBYKRSA-N

Smiles

C([C@@H](N(C([C@H](NC(C([C@H](CC)N)=O)=O)CC(C)C)=O)C([C@@H](N)[C@@H](C)CC([C@@H](N)C(C)C)=O)=O)C(C)C)(=O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD intravenous > 250mg/kg (250mg/kg)   Journal of Antibiotics. Vol. 44, Pg. 949, 1991.