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Substance Name: Dinutuximab [USAN:INN]
RN: 1363687-32-4
UNII: 7SQY4ZUD30

Notes

  • A human-mouse chimeric monoclonal antibody directed against disialoganglioside (GD2); used for treatment of refractory neuroblastoma & osteosarcoma.
  • NCI: A chimeric mouse/human monoclonal antibody with potential antineoplastic activity. Dinutuximab binds to the ganglioside GD2 and induces antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity against GD2-expressing tumor cells. GD2 is overexpressed in malignant melanoma, neuroblastoma, osteosarcoma, and small cell carcinoma of the lung. (NCI Thesaurus)
 

Classification Code

  • Antineoplastic Agents

Names and Synonyms

Name of Substance

  • Dinutuximab [USAN:INN]

Synonyms

  • APN-311
  • APN311
  • Ch 14.18
  • Ch 14.18UTC
  • CH-14.18
  • CH-14.18-UTC
  • Ch14.18
  • Ch14.18 monoclonal antibody
  • CH14.18-UTC
  • Dinutuximab
  • HSDB 8407
  • MAb ch14.18
  • Monoclonal antibody ch14.18
  • UNII-7SQY4ZUD30
  • Unituxin

Registry Numbers

CAS Registry Number

  • 1363687-32-4

FDA UNII

  • 7SQY4ZUD30

Other Registry Number

  • 339184-14-4

System Generated Number

  • 1363687324